22 August 2023: Clinical Research
Comparative Analysis of Laparoscopic Pancreatoduodenectomy in Elderly Patients: Safety, Efficacy, and Cost Evaluation
Chengfang Wang ABCDEF* , Zhijiang Wang ABDF* , Weilin Wang ADFG*DOI: 10.12659/MSM.940176
Med Sci Monit 2023; 29:e940176
Table 1 General and pathological data of patients.
| Group A (n=100) | Group B (n=60) | Group C (n=90) | P1 value | P2 value | |
|---|---|---|---|---|---|
| Sex (Male/Female) | 60/40 | 30/30 | 59/31 | 0.251 | 0.064 |
| Age (years) | 61 (53–65.75) | 73 (72–76) | 74 (72–78) | 0.376 | |
| BMI | 22.27 (19.97–24.13) | 21.80 (19.92–23.91) | 21.34 (18.94–23.51) | 0.591 | 0.187 |
| Preoperative morbidities (n,%) | 41 (41.00) | 37 (61.67) | 52 (57.78) | 0.014 | 0.735 |
| ASA score (n,%) | 0.303 | 0.661 | |||
| I–II | 91 (91.0) | 51 (85.0) | 73 (81.11) | ||
| III–IV | 9 (9.0) | 9 (15.0) | 17 (18.89) | ||
| Neoadjuvant therapy (n,%) | 2 (2.00) | 2 (3.33) | 2 (2.22) | 0.631 | 1.000 |
| History of abdominal surgery (n, %) | 16 (16.00) | 14 (23.33) | 21 (23.33) | 0.297 | 1.000 |
| Preoperative biliary drainage (n, %) | 19 (19.00) | 14 (23.33) | 31 (34.44) | 0.548 | 0.203 |
| Preoperative jaundice (n, %) | 47 (47.00) | 34 (56.67) | 55 (61.11) | 0.256 | 0.614 |
| Diagnostic characteristics (n, %) | 0.792 | 0.057 | |||
| Pancreatic cancer | 40 (40.0) | 25 (41.67) | 55 (61.11) | ||
| Cholangiocarcinoma | 4 (4.0) | 4 (6.67) | 9 (10.00) | ||
| Ampullary cancer | 14 (14.0) | 10 (16.67) | 8 (8.89) | ||
| Duodenal cancer | 20 (20.0) | 8 (13.33) | 10 (11.11) | ||
| Others | 22 (22.0) | 13 (21.67) | 8 (8.89) | ||
| Tumor size (cm) | 2.3 (1.58–3.00) | 2.5 (2.0–3.38) | 3.0 (2.0–3.5) | 0.172 | 0.071 |
| R0 resection (n, %) | 96 (96.0) | 56 (93.33) | 84 (93.33) | 0.477 | 1.000 |
| Harvest lymph nodes (n) | 14 (8.5–21) | 16 (10–21) | 16 (12–21) | 0.669 | 0.561 |
| P1: Group A vs Group B, P2: Group B vs Group C. BMI – body mass index; ASA score – American Society of Anesthesiologists classification score. | |||||