06 July 2023 : Clinical Research
Analgesic Efficacy of Combined Thoracic Paravertebral Block and Erector Spinae Plane Block for Video-Assisted Thoracic Surgery: A Prospective Randomized Clinical Trial
Lili Zhang1ABCE, Yang Hu1BEF, Hong Liu2AE, Xue Qi1CD, Hong Chen1B, Wei Cao3B, Longsheng Wang4BD, Ye Zhang
1ADEG*, Yun Wu 1ACDEG
DOI: 10.12659/MSM.940247
Med Sci Monit 2023; 29:e940247
Table 2 Secondary outcomes.
| Parameters | TPVB group (n=37) | ESPB group (n=37) | CTEB group (n=37) | P value |
|---|---|---|---|---|
| Preoperative sensory loss, n (%) | 29 (78.4%)a | 14 (37.8%) | 29 (78.4%)a | <0.001 |
| Intraoperative parameters | ||||
| Propofol consumption (μg·kg·min) | 56.9±9.5 | 59.4±13.4 | 57.2±11.9 | 0.615 |
| Remifentanil consumption (μg·kg·min) | 0.15±0.06 | 0.21±0.06b | 0.20±0.05b | <0.001 |
| Hypotension, n (%) | 15 (40.5%) | 2 (5.4%)b | 3 (8.1%)b | <0.001 |
| Postoperative parameters | ||||
| Time to extubation (min) | 7.4±4.1 | 7.2±4.8 | 6.3±3.5 | 0.503 |
| Sufentanil consumption (μg/kg) | 0.18 [0.03–0.45] | 0.30 [0.09–0.57] | 0.24 [0.09–0.45] | 0.482 |
| Analgesia satisfaction score | 3.2±0.7 | 3.1±0.7 | 3.2±0.7 | 0.751 |
| PONV (0/1/2/3), n | 26/7/2/2 | 23/4/4/6 | 20/7/6/4 | 0.459 |
| Chest tube duration (d) | 3.4±1.5 | 3.3±1.4 | 3.5±1.2 | 0.722 |
| Length of hospital stay (d) | 5.4±1.6 | 5.5±1.5 | 5.8±1.4 | 0.481 |
| PPCs, n (%) | 0 (0) | 1 (2.7%) | 2 (5.4%) | 0.772 |
| Chronic pain at 6 months, n (%) | 8/33 (24%) | 12/33 (36%)c | 4/36 (11%) | 0.047 |
| Data are represented as mean±standard deviation, median [25%–75%] or number (%). CTEB – combined thoracic paravertebral block and erector spinae plane block; ESPB – erector spinae plane block; PONV – postoperative nausea and vomiting; PPCs – postoperative pulmonary complications. TPVB – thoracic paravertebral block. a Adjusted b adjusted c adjusted | ||||