Risk Prediction for Rapidly Progressive Interstitial Lung Disease in Anti-MDA5-Positive Dermatomyositis: The CRAFT Model

15 June 2023 : Clinical Research

Jinqiang Guo^1ABCDEF, Chunli Mei^1ABCDEF, Qi Yu^2BCD, Anbin Huang^1AEF*

DOI: 10.12659/MSM.940251

Med Sci Monit 2023; 29:e940251

Background Material and Methods Results Discussion Conclusions References

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Table 2 Receiver operating characteristic analysis of significant variables.

Variables	AUC	Standard error	P values	95% CI
Variables	AUC	Standard error	P values	Upper	Lower

Mechanic’s hands	0.612	0.082	0.173	0.45	0.773
Fever	0.747	0.074	0.003	0.603	0.891
Age	0.708	0.073	0.011	0.565	0.852
CAR	0.775	0.067	0.001	0.645	0.906
FIB	0.675	0.076	0.033	0.527	0.823
TT	0.679	0.074	0.029	0.533	0.824
CRP	0.769	0.069	0.001	0.635	0.904
C4	0.694	0.076	0.018	0.546	0.842

Erythematous facial rash	0.661	0.078	0.05	0.507	0.815
PCT	0.719	0.071	0.007	0.58	0.859
RDW-SD	0.732	0.072	0.005	0.592	0.872
RDW-CV	0.746	0.069	0.003	0.611	0.88
ALB	0.696	0.075	0.017	0.55	0.842
Calcium	0.641	0.077	0.084	0.49	0.793
CD3 T cells	0.665	0.083	0.044	0.503	0.828
Ts cells	0.722	0.079	0.007	0.567	0.876
ROC – receiver operating characteristic; AUC – area under the ROC curve; CAR – C-reactive protein to albumin ratio; FIB – fibrinogen; TT – thrombin time; CRP – C-reactive protein; C4 – complement 4; PCT – procalcitonin; RDW-SD – red blood cell distribution width-standard deviation; RDW-CV – red blood cell distribution width-coefficient of variation; ALB – albumin.

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