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08 December 2023: Clinical Research

Efficacy Analysis of Neoadjuvant versus Adjuvant Cisplatin-Paclitaxel Regimens for Initial Treatment of FIGO Stages IB3 and IIA2 Cervical Cancer

Wei Tao 1DEF* , Weiqi Wang 1CDF , Jingfang Zhai 2BCF , Linlin Guo 1ABF

DOI: 10.12659/MSM.940545

Med Sci Monit 2023; 29:e940545

Table 2 Response to neoadjuvant chemotherapy for patients in the NT cohort.

Type of responseNumbers of patients
Total number of patients105
Complete response31 (30)
Partial response49 (47)
Progressive disease8 (8)
Stable disease17 (15)
Parameters are depicted as frequencies (percentages). Complete response: The absence of tumor cells and lymph nodes in pathology. Partial response:≥30% decrease in the sum of the longest diameter of the tumor in size. Progressive disease: ≥20% increase in the sum of longest diameters with an absolute increase of ≥5 mm, or detection of new lesions in pathology. Stable disease: neither partial response nor progressive disease. RECIST v1.1 was used to evaluate the response. Response was evaluated after neoadjuvant chemotherapy and before radical hysterectomy.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750