29 May 2023: Clinical Research
Pathomorphological Changes in Mammary Glands of 16 Patients Who Underwent Surgical Aquafilling Removal: A Single-Center Study
Michał Chalcarz 1ABCDEF , Beniamin Grabarek 2EF , Anna Pasiuk-Czepczyńska 3CDEF , Jakub Żurawski 4ABCDEF*DOI: 10.12659/MSM.940592
Med Sci Monit 2023; 29:e940592
Table 2 Histological changes in the breasts resulting from the Aquafilling filler reaction.
| Parameter | Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | Patient 6 | Patient 7 | Patient 8 | Patient 9 | Patient 10 | Patient 11 | Patient 12 | Patient 13 | Patient 14 | Patient 15 | Patient 16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patient age | 46 | 36 | 35 | 34 | 21 | 26 | 30 | 34 | 40 | 29 | 40 | 33 | 23 | 37 | 39 | 41 |
| The volume of injected Aquafilling into breasts (ml) | 230 ml in the left breast260 ml in the right breast | 105 ml in each breast | 200 ml in each breast | 110 ml in each breast | 100 ml in each breast | 250 ml in each breast | 150 ml in each breast | 150 ml in each breast | 250 ml in each breast | 200 ml in each breast | 150 ml in each breast | 150 ml in each breast | 160 ml in the left breast40 ml in the right breast | 200 ml in the left breast100 ml in the right breast | 100 ml in each breast | 100 ml in each breast |
| Time elapsed since noticing first side effects after filler injection (months) | 3 months | 20 months | 1 month | 14 months | did not occur | 26 months | 10 months | 19 months | Did not occur* | 14 months | 22 months | 2 months | 18 months | 3 months | 3 months | 44 months |
| Type of unfavorable symptoms | Pain in the right breast during physical effort, while raising hands, driving the car, or lying on the side; deformation of both breasts | Pain in both breasts preceding each menstruation cycle; deformation of the right breast in the upper pole | Migration of Aquafilling below the inframammary fold of both breasts | Did not occur | Did not occur | Abscess of the right breast, complexion problems; numbness of the hands; migration of filler on the left side of the chest and abdominal wall; pain in the knees | Migration of Aquafilling below the inframammary fold of both breasts | Palpable lumps and tenderness of both breasts | Did not occur* | 3 times abscess of breasts (2× right breast, 1× left breast-during breastfeeding) | Fistula of the left breast | Palpable lump under right breast; pain in both breasts preceding each menstruation cycle; numbness of the hands; fatigue; permanent elevated temperature (37.2°C) | Palpable lumps and tenderness of both breasts | Migration of filler on the left side of the chest and abdominal wall | Pain and redness of right breast; 2 times abscess of the right breast (wound contamination with ) | Migration of Aquafilling below the inframammary fold of both breasts |
| Time elapsed since Aquafilling injection to its removal procedure | 12 months after injection | 37 months after injection | 28 months after injection | 38 months after injection | 34 months after injection | 68 months after injection | 37 months after injection | 38 months after injection | 57 months after injection | 58 months after injection | 24 months after injection | 25 months after injection | 44 months after injection | 41 months after injection | 45 months after injection | 66 months after injection |
| Previous surgical procedures to remove the Aquafilling | No | No | No | No | No | Abscess evacuation from the right breast | No | No | No | No | No | No | Breast liposuction** | Breast liposuction** | Breast liposuction** | Removing Aquafilling with simultaneous breast augmentation with implants* |
| * She visited the clinic because she had seen TV reportage about patients who underwent Aquafilling breast augmentation procedure and had suffered from complications; ** procedure performed not in our hospital/clinic. | ||||||||||||||||