27 October 2023>: Clinical Research
The Impact of Sedentary Behavior on Renal Function Decline in 132,123 Middle Aged and Older Adults: A Nationwide Cohort Study
Peng Yu 12ABCDEF , Zhiyun Zhao 34BC , Li Huang 12B , Huajie Zou 12B , Xiaoyu Meng 12B , Ranran Kan 12F , Xuefeng Yu 12ABDG*DOI: 10.12659/MSM.941111
Med Sci Monit 2023; 29:e941111
Table 2 Association between sitting time and kidney function decline (n=132 123).
Quartile 1 (n=32 947) | Quartile 2 (n=27 162) | Quartile 3 (n=37 810) | Quartile 4 (n=34 204) | P for trend | |
---|---|---|---|---|---|
Cases | 894 (2.7%) | 767 (2.8%) | 1153 (3.1%) | 1076 (3.2%) | 0.003 |
Model 1 | 1 | 1.013 (0.920–1.116) | 1.079 (0.989–1.177) | 1.052 (0.963–1.150) | 0.137 |
Model 2 | 1 | 1.020 (0.925–1.126) | 1.101 (1.007–1.203) | 1.159 (1.058–1.268) | |
Model 3 | 1 | 1.002 (0.906–1.109) | 1.085 (0.990–1.189) | 1.136 (1.036–1.247) | 0.002 |
Quartiles of sitting time: 1 quartile ≤17.4 h/week, 2 quartile=17.5–27.9 h/week, 3 quartile=28.0–36.9 h/week, 4 quartile ≥37 h/week. Crude HR. Adjusted for age, sex, current smoking, current drinking. Adjusted for covariates in Model 2 plus BMI, hypertension, diabetes, dyslipidemia and MVPA. HR – hazard ratio; CI – confidence interval. |