27 October 2023: Clinical Research
The Impact of Sedentary Behavior on Renal Function Decline in 132,123 Middle Aged and Older Adults: A Nationwide Cohort Study
Peng Yu 12ABCDEF , Zhiyun Zhao 34BC , Li Huang 12B , Huajie Zou 12B , Xiaoyu Meng 12B , Ranran Kan 12F , Xuefeng Yu 12ABDG*DOI: 10.12659/MSM.941111
Med Sci Monit 2023; 29:e941111
Supplementary Table 1 Baseline characteristics of the study participants according to incident kidney function decline.
| Incident eGFR decline | P value | ||
|---|---|---|---|
| No (n=128 233) | Yes (n=3890) | ||
| Age, years | 56.48±8.94 | 62.11±9.53 | |
| Female (%) | 83860 (65.40) | 2461 (63.26) | 0.006 |
| Current smoking (%) | 19434 (15.16) | 506 (13.01) | |
| Current drinking (%) | 13685 (10.67) | 303 (7.79) | |
| MVPA (hour/week) | 1.40±4.99 | 1.41±4.56 | 0.912 |
| Sitting time (h/week) | 28.97±16.37 | 29.63±16.28 | 0.014 |
| BMI (kg/m) | 24.63±3.62 | 25.08±3.56 | |
| WC (cm) | 83.97±9.83 | 85.41±9.79 | |
| SBP (mmHg) | 132.9±20.65 | 141.1±22.72 | |
| DBP (mmHg) | 78.45±11.12 | 80.47±11.69 | |
| FPG (mmol/L) | 5.94±1.59 | 6.33±2.12 | |
| 2hPG (mmol/L) | 8.20±3.78 | 9.40±4.76 | |
| HbA1c (%) | 6.00±1.00 | 6.31±1.31 | |
| TC (mmol/L) | 4.96±1.13 | 4.84±1.43 | |
| TG (mmol/L) | 1.31 (0.93–1.91) | 1.40 (0.96–2.01) | |
| HDL-C (mmol/L) | 1.34±0.36 | 1.21±0.39 | |
| LDL-C (mmol/L) | 2.88±0.87 | 2.82±1.03 | |
| Cr (μmol/L) | 65.57±11.91 | 70.89±17.57 | |
| eGFR (mL/min/1.73 m) | 95.50±11.60 | 86.62±17.26 | |
| Prevalence of hypertension (%) | 56731 (44.24) | 2443 (62.80) | |
| Prevalence of diabetes (%) | 29319 (22.86) | 1370 (35.22) | |
| Prevalence of dyslipidemia (%) | 54163 (42.24) | 2183 (56.12) | |
| Continuous variables are expressed as the mean (standard deviation) or median (IQR), and categorical variables are expressed as the number (percentage). eGFR – estimated glomerular filtration rate; MVPA – moderate or vigorous intensity physical activity; BMI – body mass index; WC – waist circumference; SBP – systolic blood pressure; DBP – diastolic blood pressure; FPG – fasting blood glucose; 2hPG – 2 hours postprandial blood glucose; TG – triglycerides; TC – total cholesterol; HDL-C – high-density lipoprotein cholesterol; LDL-C – low-density lipoprotein cholesterol; Cr – creatinine. | |||