24 October 2023 : Clinical Research
Comparison of Nanocrystalline Hydroxyapatite Bone Graft with Empty Defects in Long Bone Fractures: A Retrospective Case-Control Study
Jonas Pawelke1ABCDEF, Vithusha Vinayahalingam1ABE, Christian Heiss12D, Matthäus Budak2E, Thaqif El Khassawna1ABCDE*, Gero Knapp2ABCDEFDOI: 10.12659/MSM.941112
Med Sci Monit 2023; 29:e941112
Table 1 Micro- and macrostructural parameters of the nanocrystalline hydroxyapatite paste (NCHA), Ostim®, compared with normal bone structure.
| Parameter | Ostim® | Adult bone |
|---|---|---|
| Pore size | <100 μm []8 | 144 μm []28 |
| Open porosity | 50.52±4.49% []8 | 50–90% trabecular bone3–12% cortical bone [,]29 |
| Density | 1.29±0.09 mg/mm []8 | 1.85±0.06 g/cm0.30±0.10 g/cm [,,]10 |
| Compressive strength | 0.24±0.05 MPa []8 | 221 MPa []31 |
| Young’s modulus | 6±3 MPa []8 | Cortical bone, 10.4 MPa []Trabecular bone, 14.8 MPa []32 |
| Specific surface | 106 m/g []13 | |
| Crystallite size | 18 nm []13 | |
| pH-value | 7.5 []13 | |
| c/p ratio | 1.67 []13 | |
| Composition | 35% hydroxyapatit, liquid solution [,]6 | 95% collagen type I []33 |