Comparison of Nanocrystalline Hydroxyapatite Bone Graft with Empty Defects in Long Bone Fractures: A Retrospective Case-Control Study

Jonas Pawelke; Vithusha Vinayahalingam; Christian Heiss; Matthäus Budak; Thaqif El Khassawna; Gero Knapp

doi:10.12659/MSM.941112

24 October 2023 : Clinical Research

Comparison of Nanocrystalline Hydroxyapatite Bone Graft with Empty Defects in Long Bone Fractures: A Retrospective Case-Control Study

Jonas Pawelke^1ABCDEF, Vithusha Vinayahalingam^1ABE, Christian Heiss^12D, Matthäus Budak^2E, Thaqif El Khassawna^1ABCDE*, Gero Knapp^2ABCDEF

DOI: 10.12659/MSM.941112

Med Sci Monit 2023; 29:e941112

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Table 6 Overview of pattern of the bone healing in post-surgery radiographs in the empty defects (ED) group and nanocrystalline hydroxyapatite paste (NCHA) group, showing statistically significant differences between the 2 treatment options.

Structure	Radiographs (days)	Average in the NHA group	Average in the ED group	Significance between groups (p-value)
Border of fracture	2 days	4.57	4.82	0.12
	28.13 days	3.17	3.6	0.06
	59.47 days	2.68	2.91	0.47
	187.46 days	1.96	2.29	0.27
	452.4 days	1.36	1.43	0.96
Gap of fracture	2 days	5.13	5.47	0.68
	28.13 days	3.57	3.59	0.94
	59.47 days	2.77	3.23	0.14
	187.46 days	2.52	2.42	0.41
	452.4 days	1.80	1.74	0.23
Articular surface	2 days	3.00	3.11	0.22
	28.13 days	2.57	2.80	0.49
	59.47 days	2.41	2.32	0.81
	187.46 days	1.79	1.93	0.75
	452.4 days	2.84	1.60	0.64
Osteosynthesis	2 days	2.26	2.02	0.14
	28.13 days	2.57	2.50	0.03
	59.47 days	1.32	2.61	0.63
	187.46 days	1.41	2.36	0.39
	452.4 days	1.13	2.17	< 0.001

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Comparison of Nanocrystalline Hydroxyapatite Bone Graft with Empty Defects in Long Bone Fractures: A Retrospective Case-Control Study

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