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24 October 2023: Clinical Research

Comparison of Nanocrystalline Hydroxyapatite Bone Graft with Empty Defects in Long Bone Fractures: A Retrospective Case-Control Study

Jonas Pawelke 1ABCDEF , Vithusha Vinayahalingam 1ABE , Christian Heiss 12D , Matthäus Budak 2E , Thaqif El Khassawna 1ABCDE* , Gero Knapp 2ABCDEF

DOI: 10.12659/MSM.941112

Med Sci Monit 2023; 29:e941112

Table 6 Overview of pattern of the bone healing in post-surgery radiographs in the empty defects (ED) group and nanocrystalline hydroxyapatite paste (NCHA) group, showing statistically significant differences between the 2 treatment options.

StructureRadiographs (days)Average in the NHA groupAverage in the ED groupSignificance between groups (p-value)
Border of fracture2 days4.574.820.12
28.13 days3.173.60.06
59.47 days2.682.910.47
187.46 days1.962.290.27
452.4 days1.361.430.96
Gap of fracture2 days5.135.470.68
28.13 days3.573.590.94
59.47 days2.773.230.14
187.46 days2.522.420.41
452.4 days1.801.740.23
Articular surface2 days3.003.110.22
28.13 days2.572.800.49
59.47 days2.412.320.81
187.46 days1.791.930.75
452.4 days2.841.600.64
Osteosynthesis2 days2.262.020.14
28.13 days2.572.500.03
59.47 days1.322.610.63
187.46 days1.412.360.39
452.4 days1.132.17< 0.001

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750