09 October 2023 : Clinical Research
A New Predictive Equation for Estimating Serum Ionized Calcium Levels in Patients on Chronic Hemodialysis
Wei-Li Hung1CE, Chi-Feng Huang23DE, Ming-Hsien Tsai45BC, Hung-Hsiang Liou6AC, Pei-Yang Liu7F, Yu-Wei Fang45AEG*DOI: 10.12659/MSM.941321
Med Sci Monit 2023; 29:e941321
Table 1 Formulae for the estimated ionized calcium level.
| Source | Formula |
|---|---|
| Our equation | 1.412 + (t[Ca] × 0.487) + (BUN × 0.002) − (Cr × 0.019) − (P × 0.034) − (Albumin × 0.327) |
| Laboratory-measured t[Ca] | t[Ca] × 0.5 |
| * | |
| Payne []9 | [t[Ca] + 0.8 × (4 - albumin)] × 0.5 |
| Clase []10 | [t[Ca] + 0.72 × (3.5 - albumin)] × 0.5 |
| Jain []11 | [t[Ca] + 0.8 × (3 - albumin)] × 0.5 |
| Ferrari []12 | [t[Ca] + 1.6 × (4 - albumin) + 0.56 × (1.5 − 0.32 × P)] × 0.5 |
| * The formulae yielding a total corrected calcium will multiply 0.5 to estimate the ionized calcium level. t[Ca] – total calcium; Cr – creatinine; BUN – blood urea; P – phosphate. | |






