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09 October 2023: Clinical Research

A New Predictive Equation for Estimating Serum Ionized Calcium Levels in Patients on Chronic Hemodialysis

Wei-Li Hung 1CE* , Chi-Feng Huang 23DE* , Ming-Hsien Tsai 45BC , Hung-Hsiang Liou 6AC , Pei-Yang Liu 7F , Yu-Wei Fang 45AEG*

DOI: 10.12659/MSM.941321

Med Sci Monit 2023; 29:e941321

Table 1 Formulae for the estimated ionized calcium level.

SourceFormula
Our equation1.412 + (t[Ca] × 0.487) + (BUN × 0.002) − (Cr × 0.019) − (P × 0.034) − (Albumin × 0.327)
Laboratory-measured t[Ca]t[Ca] × 0.5
*
 Payne []9 [t[Ca] + 0.8 × (4 - albumin)] × 0.5
 Clase []10 [t[Ca] + 0.72 × (3.5 - albumin)] × 0.5
 Jain []11 [t[Ca] + 0.8 × (3 - albumin)] × 0.5
 Ferrari []12 [t[Ca] + 1.6 × (4 - albumin) + 0.56 × (1.5 − 0.32 × P)] × 0.5
* The formulae yielding a total corrected calcium will multiply 0.5 to estimate the ionized calcium level.
t[Ca] – total calcium; Cr – creatinine; BUN – blood urea; P – phosphate.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750