09 October 2023 : Clinical Research
A New Predictive Equation for Estimating Serum Ionized Calcium Levels in Patients on Chronic Hemodialysis
Wei-Li Hung1CE, Chi-Feng Huang23DE, Ming-Hsien Tsai45BC, Hung-Hsiang Liou6AC, Pei-Yang Liu7F, Yu-Wei Fang45AEG*DOI: 10.12659/MSM.941321
Med Sci Monit 2023; 29:e941321
Table 3 Determinants of the serum ionized calcium level in patients on chronic hemodialysis.
| Parameter | Crude | Multivariable | ||
|---|---|---|---|---|
| β (95% CI) | P | β (95% CI) | P | |
| Age (per 1 years) | 0.001 (−0.003, 0.005) | 0.578 | ||
| Males [vs female] | −0.133 (−0.043, −0.223) | 0.004 | ||
| Kt/V (per 1 unit) | 0.484 (0.260, 0.708) | <0.001 | ||
| Blood nitrogen (per 1 mg/dL) | 0.001 (−0.002, 0.003) | 0.784 | 0.002 (0.001, 0.003) | 0.001 |
| Creatinine (per 1 mg/dL) | −0.019 (−0.037, −0.001) | 0.040 | −0.019 (−0.028, −0.008) | <0.001 |
| Sodium (per 1 mEq/L) | 0.014 (−0.001, 0.028) | 0.061 | ||
| Potassium (per 1 mEq/L) | 0.054 (−0.015, 0.123) | 0.125 | ||
| Calcium (per 1 mg/dL) | 0.438 (0.413, 0.464) | <0.001 | 0.487 (0.465, 0.509) | <0.001 |
| Phosphate (per 1 mg/dL) | −0.023 (−0.058, −0.012) | 0.192 | −0.034 (−0.052. −0.016) | <0.001 |
| Albumin level (per 1 g/dL) | −0.044 (−0.157, 0.069) | 0.445 | −0.327 (−0.386, −0.268) | <0.001 |
| Ln (Triglyceride) (per 1 unit) | −0.037 (−0.112, 0.038) | 0.330 | ||
| Total cholesterol (per 1 mg/dL) | 0.001 (0.001, 0.002) | 0.036 | ||
| Hemoglobin (per 1 g/dL) | −0.001 (−0.034, 0.312) | 0.944 | ||
| Alk-P (per 1 U/L) | 0.001 (−0.001, 0.002) | 0.210 | ||
| ALT (per 1 U/L) | −0.002 (−0.007, 0.004) | 0.489 | ||
| AST (per 1 U/L) | 0.001 (−0.005, 0.006) | 0.902 | ||
| Iron (per 1 g/dL) | −0.001 (−0.002, 0.001) | 0.538 | ||
| Ln (Ferritin) (per 1 unit) | 0.086 (0.041, 0.131) | <0.001 | ||
| Transferrin saturation (per 1%) | 0.001 (−0.004, 0.004) | 0.978 | ||
| CI – confidence interval; Kt/V – urea kinetics; Ln – natural log transformation; Alk-P – alkaline phosphatase; ALT – alanine aminotransferase; AST – aspartate aminotransferase. | ||||