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24 November 2023: Clinical Research

Prosthodontic Rehabilitation’s Role in Alleviating Anxiety and Depression in Mucormycosis-Induced Maxillectomy Patients Post-COVID-19

Abdulelah Sameer Sindi 1ACDEG , Lakshya Kumar 2ABCEF* , Aditi Verma 2ABCEF , Uma Shanker Pal 3ABCEF , Mohammed E. Sayed 4ACDEF , Khurshid Mattoo 4ACDEF* , Mohamed S.M. Morsy 4ACDEF , Suheel Manzoor Baba 1ACDEF , Imran Khalid 5ACDEG , Fawaz A.H. Baig 5ACDEG , Sulphi Abdul Basheer 5ACDEG , Mohammad Z. Kota 5ACDEG , Shabina Shafi 6CDEF

DOI: 10.12659/MSM.941488

Med Sci Monit 2023; 29:e941488

Table 2 Comparative differences in mean values of Appearance Anxiety (AAI) and Depression Scale (PHQ-9) between various maxillectomy/treatment groups/subgroups at 4 treatment time intervals.

ParametersMaxillectomy/treatment typesSexNT0 (Baseline)M±SDT1 (2 week)M±SDT2 (6 month)M±SDT3 (1 year)M±SDOne-way ANOVA
Chi-Square (χ2)dfP value
Anxiety (BIA, BDD)STM(U)ObturatorM622.17 ±1.1619.67 ±2.0613.67 ±1.0312.17 ±1.1616.913.00074***
F823.13 ±1.2420.87 ±0.9917.25 ±0.8813.63 ±1.6823.433.00003***
STM(B)Zygomatic ImplantM930.56 ±1.3327.44 ±1.7417.78 ±1.4813.44 ±1.3327.003.00001***
F532.6 ±1.1428.6 ±1.1521.2 ±1.3017.4 ±1.5214.463.00234**
TM(U)ObturatorM526.0 ±1.7321.00 ±1.8717.6 ±1.1415.8 ±1.6413.383.00388**
F527.00 ±1.5824.6 ±2.0720.2 ±1.4817.4 ±1.1414.463.0023**
TM(B)Zygomatic ImplantM1033.0 ±1.4126.10 ±1.3720.6 ±1.5718.2 ±1.2229.433.00001***
F933.78 ±1.3929.0 ±1.5022.67 ±2.0619.78 ±1.3025.933.00001***
TMOE (U)Obturator, Ocular, OrbitalM335.33 ±2.0831.66 ±1.1526.33 ±2.0822.33 ±1.1515.003.00182**
Depression SeveritySTM(U)ObturatorM611.0 ±2.3611.5 ±1.765.16 ±0.984.16 ±1.7214.983.0019**
F810.5 ±1.6011.62 ±1.508.0 ±1.196.75 ±1.6614.583.00221**
STM(B)Zygomatic ImplantM920.11 ±2.1422.11 ±1.6113.88 ±1.265.12 ±1.7627.003.00001***
F520.2 ±1.9221.6 ±1.6716.8 ±1.489.6 ±0.8915.003.00182**
TM(U)ObturatorM512.8 ±1.6315.8 ±1.307.6 ±1.344.8 ±1.3114.043.00285**
F511.6 ±1.9414.0 ±1.878.6 ±2.704.8 ±1.3013.383.00388**
TM(B)Zygomatic ImplantM1020.2 ±1.6821.9 ±1.4414.7 ±2.059.1 ±1.8527.813.00001***
F921.33 ±1.8023.0 ±1.3214.22 ±1.788.78 ±1.0925.503.00001***
TMOE (U)Obturator, Ocular, OrbitalM320.33 ±2.0822.0 ±2.6420.0 ±1.7317.33 ±2.0810.143.01741**
N – number of subjects; M – mean; SD – standard deviation; STM(U) – subtotal maxillectomy unilateral; STM(B) – subtotal maxillectomy bilateral; TM(U) – total maxillectomy unilateral; TM(B) – total maxillectomy bilateral; TMOE (U) – total maxillectomy with orbital exenteration. T0 – observation before prosthesis (3–4 months’ after maxillectomy); T1 – observation at 2 weeks after delivery of respective prosthesis (obturator/implant-supported prosthesis); T2 – observation at 6 months; T3 – observation at 12 months.
Score from 0 to 19 – normal, 19 to 27 –clinical BIA, 27 and above - diagnosis of BDD.
Total score in the range of 0 to 27. Degree of severity determined on cut point scores as 5,10,15 and 20 representing the degree of symptoms as mild, moderate, moderately severe, and severe, respectively.
Friedman’s test for repeated measure analysis of variance after adjustment/correction of Q (probability distribution).
* All differences at various time intervals in each group were considered to be statistically significant if the probable P value was ≤0.05: Levels of significance: NS (not significant)=P≤0.05; * Significant=P≤0.05; ** Very significant=P≤0.01; *** Highly significant=P≤0.001.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750