Changes in Gut Microbiota at 1-60 Days in 92 Preterm Infants in a Neonatal Intensive Care Unit Using 16S rRNA Gene Sequencing

29 November 2023 : Laboratory Research

Yuanyuan Chen^1BCDE, Yanbo Lu^2CE, Ting Wang^1CDF, Junhua Wu^2AEFG*, Beirong Yu^2ABG

DOI: 10.12659/MSM.941560

Med Sci Monit 2023; 29:e941560

Background Material and Methods Results Discussion Conclusions References

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Table 4 Analysis of alpha diversity at different time points.

	Chao1	Observed species	Shannon	Simpson
D1	285.71±126.09	240.71±113.09	1.50±0.64	0.35±0.18
D3	284.58±187.31	237.39±181.77	1.67±0.81	0.42±0.23
D7	229.06±100.06	182.80±88.51	1.86±0.86	0.50±0.23
D14	198.72±76.42	153.96±70.62	2.15±0.84	0.59±0.21
D21	211.27±86.00	166.47±77.35	2.35±0.93	0.63±0.22
D28	205.83±71.76	161.43±65.31	2.31±0.92	0.61±0.24
D60	268.25±108.18	215.01±101.86	2.39±1.04	0.58±0.25
F value	7.20	7.98	7.82	16.58
P value	<0.001^#	<0.001^#	<0.001^#	<0.001^*
^* One-way ANOVA; ^# Welch’s ANOVA.

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