07 December 2023: Clinical Research
Prognostic Factors for Uterine Sarcoma and Carcinosarcoma: Insights from a 10-Year Follow-Up Study
Beata Kotowicz 1ACDEF* , Anna Dańska-Bidzińska 2ABDEG , Małgorzata Fuksiewicz 1BCDE , Anna Nasierowska-Guttmejer 3BC , Dorota Raczkiewicz 4C , Mariusz Gujski 5BEF , Szymon Piątek 6B , Mariusz Bidziński 6AEGDOI: 10.12659/MSM.941562
Med Sci Monit 2023; 29:e941562
Table 5 Significant prognostic factors for survival in univariate and multivariate analysis in the analyzed group of patients.
| Prognostic factor | Univariate models | Unrestricted multivariate model | Restricted multivariate model | |||
|---|---|---|---|---|---|---|
| HR | p | HR | p | HR | p | |
| Old age (60+ vs | 2.39 | 0.013 | 2.02 | 0.074 | 2.51 | 0.010 |
| Ki 67 (high vs low) | 20.83 | 0.048 | 2.06 | 0.484 | ||
| Ki 67 (high vs medium) | 1.05 | 0.953 | 1.68 | 0.817 | ||
| p53 (high vs low expression) | 14.67 | 0.008 | 12.05 | 0.022 | 15.31 | 0.007 |
| ER (low vs high expression) | 3.55 | 0.009 | 1.37 | 0.613 | ||
| PR (low vs high expression | 5.08 | 0.026 | 1.36 | 0.773 | ||
| CA 125 IU/mL | 5.35 | 0.035 | 2.32 | 0.021 | 4.017 | 0.045 |
| IL-8 pg/mL | 7.84 | 0.024 | 2.19 | 0.028 | ||
| HR – hazard ratio in Cox’s regression model; n/a – it is not possible to estimate, because all the patients with IA survived. | ||||||