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24 August 2023: Clinical Research

Assessing the Impact of Hepatitis B Elimination Program on Maternal-Infant Health in West Java, Indonesia: A Cross-Sectional Study

Anita Deborah Anwar 1ABCDEFG , Annisa Dewi Nugrahani 1ABCDEF* , Dhanny Primantara Johari Santoso 1ABCDE , Muhammad Alamsyah Aziz 1ADEF , Lia Ulfah 2BCD , Asep Surachman 3B

DOI: 10.12659/MSM.941639

Med Sci Monit 2023; 29:e941639

Table 5 Factors associated with infants’ HBsAg status.

VariablesTotal (n=59 for Mother; n=62 for Infants)Infants’ HBsAg statusP valueCorrelation (r)OR
HBsAg (+)HbsAg (−)
1.000N/AN/A
 Mean±SD5928.00±1.0030.23±6.48
 Median (range)28 (27–29)30 (20–42)
0.1000.3800.363 (0.002–0.815)
 Singleton56155
 Multiple312
1.0000.050N/A
 At term (≥37 weeks)54252
 Preterm (505
0.9640.170N/A
 Spontaneous48147
 Assisted vaginal delivery202
 Cesarean delivery918
N/AN/AN/A
 Reactive59257
 Non-reactive000
1.0000.080N/A
 Reactive49247
 Non-reactive10010
0.1440.0640.500 (0.030–8.439)
 Yes39138
 No20119
* 0.1060.326 (0.019–5.554)
 Yes44143
 No24114
1.0000.043N/A
 Yes56254
 No303
* For numerical data, the value was tested with the unpaired test if the data were normally distributed, and with an alternative Mann-Whitney test if the data were not normally distributed. For categorical data, the value was calculated based on the chi-square test with an alternative Exact Fisher’s exact test if the conditions of the chi-square test were not met. For the delivery method group, analysis was conducted using the Kolmogorov-Smirnov test. A correlation test was conducted using the Cramer’s V test, except for the delivery method, which was conducted using the Contingency Coefficient test. Statistical significance was set at value
HBIG – hepatitis B immune globulin; HBV vaccine – hepatitis B vaccine; HBsAg – hepatitis B surface antigen; OR – odds ratio.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750