18 November 2023 : Laboratory Research
Enhanced Proliferation and Adhesion Marker Gene Expression in Fibroblast Cells: Evaluating the Efficacy of a Non-Surgical Treatment for Urogenital Fistula
Efriyan Imantika
12ABCDEF*, R.M. Sonny Sasotya1ADEF, Edwin Armawan1ACDEF, Kevin D. Tjandraprawira1DEF, Rodiani Rodiani2AEF, Taufiqurrahman Rahim2AEF
DOI: 10.12659/MSM.941641
Med Sci Monit 2023; 29:e941641
Table 2 One-way ANOVA analysis of TGF-β, JAMs, and LOX gene expression between 4 groups treated with a mucoadhesive bilayer membrane combined with: (1) ALSR; (2) estradiol; (3) arginine+glutamine; (4) control (cultured cells only).
| Sum of squares | df | Mean square | F | p | |
|---|---|---|---|---|---|
| β | |||||
| Between Groups | 724.3 | 3 | 241.45 | 2.33 | 0.15 |
| Within Groups | 830.9 | 8 | 103.86 | ||
| Total | 1555.2 | 11 | |||
| β | |||||
| Between Groups | 32618.4 | 3 | 10872.9 | 2.7 | 0.12 |
| Within Groups | 32701.4 | 8 | 4087.7 | ||
| Total | 65319.7 | 11 | |||
| Between Groups | 472865.7 | 3 | 157621.9 | 1.18 | 0.38 |
| Within Groups | 1071086.6 | 8 | 133885.8 | ||
| Total | 1543952.3 | 11 | |||
| Between Groups | 102186.7 | 3 | 34062.2 | 21.1 | 0.001* |
| Within Groups | 12895.3 | 8 | 1611.9 | ||
| Total | 115082.04 | 11 | |||
| Between Groups | 11834.4 | 3 | 3944.8 | 2.4 | 0.14 |
| Within Groups | 13071.3 | 8 | 1633.9 | ||
| Total | 24905.7 | 11 | |||
| Between Groups | 32030.2 | 3 | 10676.75 | 12.3 | 0.002* |
| Within Groups | 6949.7 | 8 | 868.7 | ||
| Total | 38979.9 | 11 | |||
| ANOVA – analysis of variance; TGF-β – tumor growth factor beta; JAMs – junctional adhesion molecules; LOX – lysil oxidase; ALSR – lyophilized radiation-sterilized amnion. * | |||||