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07 October 2023: Review Articles

Optimizing Delivery Strategies in Eclampsia: A Comprehensive Review on Seizure Management and Birth Methods

Marzena Laskowska 1AEF* , Anna Bednarek 2EF

DOI: 10.12659/MSM.941709

Med Sci Monit 2023; 29:e941709

Table 1 The first choice of antihypertensive drugs with rapid effect by venous infusion is used for hypertensive emergencies in eclamptic women [31–34].

DrugMechanism of activityDosageThe time when the drug starts its actionDuration of action of the drugSide effects/contraindications
Hydralazine2.5–5mg5–20 minutes from administration [–]31 2–6 hoursdo not use in case of tachycardia above 100 beats per minute
LabetalolStarting with a dose of 10–20 mg during the first 2 min and can be repeated with a dose of 20 mg, 40–60 mg, or 80 mg every 20–30 min, or up to a maximum dose of 300mg/day or continuous intravenous injection, in the starting dose of 1–2 mg/min, and subsequent dose of 5–10 mg/h, up to a dose of 300 mg/day [–]31 After 5 minutes peak activity is reached in 10–20 minutes after its administration [–]31 6 hoursmay occur bradycardia in a mother and fetus [–]31
mg – milligram; mg/h – milligram per hour; BP – blood pressure; min – minute; h – hour; HR – heart rate.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750