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20 September 2023 : Clinical Research  

Early Echocardiography and ECG Changes Following Radiotherapy in Patients with Stage II-III HER2-Positive Breast Cancer Treated with Anthracycline-Based Chemotherapy with or without Trastuzumab-Based Therapy

Radu Valeriu Toma
  • A Study design/planning
  • B Data collection/entry
  • C Data analysis/statistics
  • G Funds collection
" data-author="4365589">12ABCG
, Zgura Anca1E, Oana Gabriela Trifănescu
  • A Study design/planning
" data-author="4365591">12A
, Laurenția Nicoleta Galeș
  • D Data interpretation
" data-author="4365592">12D*
, Antonia Ruxandra Folea
  • C Data analysis/statistics
  • D Data interpretation
  • E Preparation of manuscript
  • F Literature analysis/search
" data-author="4365593">2CDEF
, Loredana Stanca3B, Liviu Bîlteanu
  • 3Department of Preclinical Science, Faculty of Veterinary Medicine, University of Agronomic Sciences and Veterinary Medicine, Bucharest, Romania
  • 4Laboratory of Molecular Nanotechnologies, National Institute for Research and Development in Microtechnologies, Voluntary, Romania
    • A Study design/planning
    • B Data collection/entry
    • C Data analysis/statistics
    • D Data interpretation
    • E Preparation of manuscript
    • F Literature analysis/search
    " data-author="4365595">234ABCDEF
    , Rodica M. Anghel1A

    DOI: 10.12659/MSM.941754

    Med Sci Monit 2023; 29:e941754

    Supplementary Table 8 Muscular and vascular structures of the heart at risk in breast tumor irradiation - descriptive statistics (mean value, standard deviation, range, minimum and maximum values, 25th, 33rd, 50th or median, 67th and 75th percentiles) for the dosimetric parameters determined in the case of these structures, namely mean dose (DMed), maximum dose (DMax), V25 and V30. The values are expressed in cGy.

    Muscular structures
    HeartLV
    DMedDMaxV25DMedDMaxV25V30
    Mean534.313590.615.75711.763116.2110.388.93
    SD387.141747.695.92608.752225.7011.5110.86
    Range1453.205696.0017.801919.205631.1038.0035.60
    Min26.803.000.009.9027.500.000.00
    Max.1480.005699.0017.801929.105658.6038.0035.60
    Percentiles2595.052317.950.0025.5083.700.000.00
    33185.842824.100.02250.441174.670.280.17
    50593.604478.804.30666.704368.308.204.80
    67724.774605.869.671070.484663.4913.7511.63
    75812.304929.3010.651178.754885.5018.0015.70
    Mean1835.272739.8933.2832.06379.15521.341.410.04
    SD1631.662105.6735.3435.43477.47620.527.870.23
    Range4574.605152.8096.4096.102251.902957.1043.801.30
    Min10.0017.300.000.0054.1077.900.000.00
    Max.4584.605170.1096.4096.102306.003035.0043.801.30
    Percentiles2538.7567.500.000.00114.20199.880.000.00
    33527.16995.680.000.00144.02212.820.000.00
    501324.803839.1022.7013.45167.30273.200.000.00
    673098.024464.8663.5266.60252.56315.950.000.00
    753270.654694.8570.7068.65477.90531.130.000.00
    Mean278.08323.11203.37292.31
    SD294.75332.24224.37285.92
    Range1119.501236.001008.001135.00
    Min19.5021.000.000.00
    Max.1139.001257.001008.001135.00
    Percentiles2564.5573.2531.3049.40
    33112.23146.9655.5896.41
    50175.90206.30136.30211.50
    67230.58267.26173.86310.07
    75294.10324.80271.35406.85
    LV – left ventricle, LAD – left anterior descendent artery, RCA – right circumflex artery, LCA – left circumflex artery, ACX – anterior circumflex artery.

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    Medical Science Monitor eISSN: 1643-3750
    Medical Science Monitor eISSN: 1643-3750