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20 September 2023: Clinical Research

Early Echocardiography and ECG Changes Following Radiotherapy in Patients with Stage II–III HER2-Positive Breast Cancer Treated with Anthracycline-Based Chemotherapy with or without Trastuzumab-Based Therapy

Radu Valeriu Toma 12ABCG , Zgura Anca 1E , Oana Gabriela Trifănescu 12A , Laurenţia Nicoleta Galeş 12D* , Antonia Ruxandra Folea 2CDEF , Loredana Stanca 3B , Liviu Bîlteanu 234ABCDEF* , Rodica M. Anghel 1A

DOI: 10.12659/MSM.941754

Med Sci Monit 2023; 29:e941754

Table 5 Association of the presence of changes in electrocardiographic findings with clinical factors during monitoring.

VariableOR95% CIp-valueRR95% CI
Height ≥1.64 m7.50(1.50, 37.394)0.0141.76(1.50, 2.06)
New T-wave modification5.20(3.04, 210.93)0.00311.43(1.66, 78.88)
[Pre-existing] modifications of T-wave in posterior leads5.56(1.08, 83.07)0.0434.60(0.72, 29.22)
Thyroid disease13.33(2.16, 81.94)0.0056.28(3.84, 10.29)
Age ≥58 yrs9.45(1.07, 83.06)0.0437.24(2.99, 17.50)
Presence of chronic infections, inflammatory or thyroid-related diseases8.20(1.54, 43.47)0.0135.00(2.98, 8.37)
New ST junction (J) or ST segment depression6.00(2.49, 86.03)0.0033.32(0.99, 11.1)
New T-wave modification5.19(2.98, 57.00)0.0012.03(1.24, 3.33)
New ST junction (J) or ST segment depression6.00(5.01, 280.90)2.55(1.04, 6.26)
New T-wave modification5.19(1.60, 132.38)0.0171.39(1.04, 1.86)

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750