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22 February 2024: Clinical Research

Effectiveness of Glutamine Oral Care in Reducing Oral Mucositis and Improving Oral Health After Neurosurgery: A Randomized Controlled Trial with Microbiome Analysis

Yan Gao DE , Hong Yang B , Xiaohong Zhang C , Ying Ma DF , Ling Wang AE*

DOI: 10.12659/MSM.942585

Med Sci Monit 2024; 30:e942585

Table 3 General information.

ControlGlutamineCompound chlorhexidineP
Age48.57±17.3650.93±15.1850.13±14.430.5583
Length of stay (day)12.07±8.8610.82±6.8111.81±8.340.5118
Gender (n, %)
 Male59 (59.00%)61 (61.00%)60 (60.00%)0.9592
 Female41 (41.00%)39 (39.00%)40 (40.00%)
Diagnosis (n, %)
 Cerebral hemorrhage52 (52.00%)49 (49.00%)50 (50.00%)0.9730
 Brain tumor34 (34.00%)39 (39.00%)37 (37.00%)
 Brain trauma6 (6.00%)7 (7.00%)7 (7.00%)
 Other8 (8.00%)5 (5.00%)6 (6.00%)
Smoke (n, %)48 (48.00%)36 (36.00%)41 (41.00%)0.2243
Hypertension (n, %)13 (13.00%)11 (11.00%)15 (15.00%)0.2731
Alcohol use (n, %)22%25%23%0.1754
BMI, kg/m23.70±3.8924.31±3.9723.91±4.220.5541

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750