22 April 2024 : Clinical Research
Predicting Acute Cardiovascular Complications in COVID-19: Insights from a Specialized Cardiac Referral Department
Michał Machowski
1ABCDEF, Aisha Ou-Pokrzewińska1BCDEF, Katarzyna Perzanowska-Brzeszkiewicz 1BCDEF, Magdalena Gałecka-Nowak 1BDE, Szymon Pacho1BDE, Mateusz Jermakow 1BCDE*, Agnieszka Wójcik1BDE, Milena Zoruk1BDE, Andrzej Pruszczyk 1BDE, Karol Deutsch1BDE, Marek Roik 1BDE, Andrzej Łabyk 1BDE, Piotr Palczewski 2ABDEF, Piotr Pruszczyk 1ABCDEF
DOI: 10.12659/MSM.942612
Med Sci Monit 2024; 30:e942612
Table 4 Optimal cut-off points for the diagnosis of acute cardiovascular diseases.
| Parameter [unit] | Optimal cut-off point | AUC (95% CI) | Sensitivity (%) | Specifity (%) | PPV (%) | NPV (%) | P-value |
|---|---|---|---|---|---|---|---|
| D-dimer [ng/ml] | 4968.5 | 0.850 (0.765; 0.935) | 69.4 | 96.2 | 80.6 | 93.3 | <0.001 |
| NT-proBNP [pg/ml] | 8970.0 | 0.692 (0.502; 0.883) | 54.5 | 86.5 | 25.0 | 95.8 | 0.004 |
| Left ventricle ejection fraction [%] | 33.5 | 0.948 (0.899; 0.996) | 86.7 | 91.2 | 61.9 | 97.6 | <0.001 |
| AUC – area under curve; CI – confidence interval; LVEF – left ventricle ejection fraction; PPV – positive predictive value; NPV – negative predictive value; ACS – acute coronary syndrome; AMyo – acute myocarditis; APE – acute pulmonary embolism; CAD – coronary artery disease; CHF – congestive heart failure; CRP – C-reactive protein; MEWS – Modified Early Warning Score. | |||||||