08 July 2024 : Clinical Research
Optimal Surgical Approaches for Thyroid Cancer: A Comparative Analysis of Efficacy and Complications
Abbas Aras
1ABDEF*, Ali R. Karayıl 2BCG
DOI: 10.12659/MSM.942619
Med Sci Monit 2024; 30:e942619
Table 3 Summary of patients’ and tumor characteristics with regard to groups.
| Thyroidectomy | P | |||
|---|---|---|---|---|
| CTx-HTx (n=60) | TTx (n=60) | RTx-TTx (n=47) | ||
| Age | 39.38±13.12 | 41.60±14.14 | 44.00±12.98 | 0.214 |
| ≤45 | 43 (71.7%) | 37 (61.7%) | 26 (55.3%) | 0.205 |
| >45 | 17 (28.3%) | 23 (38.3%) | 21 (44.7%) | |
| Sex | ||||
| Female | 46 (76.7%) | 46 (76.7%) | 38 (80.9%) | 0.842 |
| Male | 14 (23.3%) | 14 (23.3%) | 9 (19.1%) | |
| Pathology result, Main side(1) | ||||
| Benign | 0 (0.0%) | 15 (25.0%) | 19 (48.7%) | |
| Malign | 60 (100.0%)a | 45 (75.0%)b | 20 (51.3%)c | |
| Pathology result, Opposite side(2) | ||||
| Benign | 46 (76.7%) | 52 (86.7%) | 36 (76.6%) | 0.295 |
| Malign | 14 (23.3%) | 8 (13.3%) | 11 (23.4%) | |
| Calcium (mg/dL) | ||||
| Preoperative | 9.47±0.48 | 9.61±0.44 | 9.43±0.62 | 0.160 |
| Postoperative | 8.73±0.56a | 8.36±0.66b | 8.44±0.78ab | |
| (within groups) | ||||
| Change in calcium | −0.73±0.61a | −1.25±0.65b | −0.99±0.79ab | |
| Transient hypocalcemia | 6 (10.0%) | 16 (26.7%) | 8 (17.0%) | 0.058 |
| Permanent hypocalcemia | 0 (0.0%) | 1 (1.7%) | 2 (4.3%) | 0.257 |
| Recurrent laryngeal nerve injury | 0 (0.0%) | 0 (0.0%) | 1 (2.1%) | 0.277 |
| Length of stay in hospital | ||||
| One day | 54 (90.0%) | 43 (71.7%) | 34 (72.3%) | |
| Two days or more | 6 (10.0%)a | 17 (28.3%)b | 13 (27.7%)ab | |
| Data are given as mean±standard deviation or median (minimum–maximum) for continuous variables according to normality of distribution and as frequency (percentage) for categorical variables. a, b, c Same letters denote the lack of statistically significant difference between groups. (1) Here, pathology results of hemithyroidectomy specimens for CTx-HTx, postoperative pathology results of the FNAC performed side for TTx and postoperative pathology result of the side that had FNAC before the first surgery for RTx-TTx are meant. (2) Here, pathology results of complementary thyroidectomy specimen for CTx-HTx, postoperative pathology results of the contralateral lobe for TTx, and pathology results after revision surgery for RTx-TTx are meant. CTx-HTx – the patients who had thyroidectomy performed after hemithyroidectomy; TTx – the patients who had total thyroidectomy without revision surgery; RTx-TTx – the patients with revision thyroidectomy after total thyroidectomy. | ||||