21 May 2024 : Clinical Research
Protective Role of TRPC3 Gene Polymorphism (rs10518289) in Obstructive Sleep Apnea Hypopnea Syndrome Among Hypertensive Patients
Yu Li1CDE, Reyihanguli Shataer2BC, Yulan Chen3ABCFG*, Xiaoli Zhu4B, Xiaojing Sun5ABDOI: 10.12659/MSM.942667
Med Sci Monit 2024; 30:e942667
Table 3 Hardy-Weinberg equilibrium for EH group and EH+OSHAS group.
| TRPC3 locus | Genotype | EH groug (n=74) | EH+OSHAS group (n=299) | ||||
|---|---|---|---|---|---|---|---|
| Actual | Expected | P value | Actual | Expected | P value | ||
| Rs953691 | GG | 23 | 20 | 0.254 | 99 | 91 | 0.063 |
| GT | 32 | 36 | 132 | 148 | |||
| TT | 19 | 19 | 68 | 60 | |||
| Rs10518289 | CC | 23 | 20 | 0.254 | 48 | 45 | 0.465 |
| CG | 32 | 37 | 136 | 142 | |||
| GG | 19 | 16 | 115 | 112 | |||
| Rs2292232 | CC | 25 | 22 | 0.184 | 97 | 90 | 0.129 |
| CT | 31 | 37 | 135 | 148 | |||
| TT | 18 | 15 | 67 | 60 | |||
| Rs4995894 | AA | 55 | 54 | 0.626 | 220 | 218 | 0.437 |
| CA | 17 | 18 | 71 | 74 | |||
| CC | 2 | 1 | 8 | 6 | |||
| Rs951974 | AA | 19 | 16 | 0.173 | 68 | 62 | 0.185 |
| GA | 31 | 37 | 137 | 148 | |||
| GG | 24 | 21 | 94 | 88 | |||
| Rs4292355 | CC | 50 | 52 | 0.096 | 205 | 204 | 0.700 |
| CT | 24 | 20 | 84 | 86 | |||
| TT | 0 | 2 | 10 | 9 | |||