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21 May 2024: Clinical Research

Protective Role of TRPC3 Gene Polymorphism (rs10518289) in Obstructive Sleep Apnea Hypopnea Syndrome Among Hypertensive Patients

Yu Li 1CDE* , Reyihanguli Shataer 2BC* , Yulan Chen 3ABCFG* , Xiaoli Zhu 4B , Xiaojing Sun 5AB

DOI: 10.12659/MSM.942667

Med Sci Monit 2024; 30:e942667

Table 5 Logistic regression analysis of factors influencing OSAHS in patients with essential hypertension.

BSEWald χ2P valueOR value95% CI
Rs10518289 dominant model (CC vs CG+GG)−0.7740.3484.9610.0260.4610.233~0.911
Genger−0.0740.4862.3150.1280.4770.184~1.238
Smoking history0.1870.3780.2440.6211.2050.575~2.529
Alcohol history−0.3310.3830.7490.3871.3930.659~2.949
Hypertension history−0.0020.0030.6030.4380.9980.993~1.003
Age0.0740.02013.8330.0001.0771.036~1.120
FPG−0.0700.1370.2570.6120.9330.713~1.221
BMI0.2350.05716.9190.0001.2651.131~1.415
TG0.3100.2251.9040.1681.3640.878~2.119
TC0.0300.5610.0030.9581.0300.343~3.092
HDL-C0.5240.6820.5890.4431.6880.443~6.432
LDL-C−0.1050.6170.0290.8650.9000.269~3.016
GHb0.0410.2400.0290.8661.0420.651~1.668
urea−0.0390.1230.1020.7490.9610.755~1.224
Creatinine−0.0140.0111.5000.2210.9860.965~1.008
24-h MSBP−0.0020.0200.0130.9101.0020.964~1.042
24-h MDBP−0.0050.0260.0390.8440.9950.946~1.046
EH=0, EH+OSAHS=1; genger (male=1, female=0); smoking history (yes=1, no=0); alcohol history (yes=1,no=0); Rs10518289 genotype (CC=1,CG+GG=2).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750