23 February 2024>: Clinical Research
Urinary Concentration of Renal Biomarkers in Healthy Term Neonates: Gender Differences in GST-pi Excretion
Monika Kamianowska 1ACDE* , Agnieszka Rybi-Szumińska 2AD , Aleksandra Kamianowska 2CEF , Mateusz Maciejczyk 3C , Anna Zubrzycka 1B , Joanna Nazarko 1B , Anna Wasilewska 2ACDEDOI: 10.12659/MSM.942819
Med Sci Monit 2024; 30:e942819
Table 4 The biomarkers’ concentrations and the values of the biomarker/Cr ratios in the cesarean- and vaginal-born neonates.
Parameters | Cesarean-born neonates (N=39) | Vaginal-born (N=41) | p |
---|---|---|---|
Median (Q1-Q3) | |||
Calbindin (ng/ml) | 116.49 (28.32–319.97) | 183.54 (31.85–461.54) | NS |
Calbindin/cr. (ng/mg cr.) | 168.68 (91.63–501.63) | 204.90 (36.17–600.53) | NS |
KIM-1 (ng/ml) | 0.03 (0.01–0.08) | 0.11 (0.03–0.17) | NS |
KIM-1/cr. (ng/mg cr.) | 0.07 (0.03–0.17) | 0.13 (0.04–0.18) | NS |
MCP-1 (ng/ml) | 0.02 (0.01–0.05) | 0.03 (0.02–0.09) | NS |
MCP-1/cr. (ng/mg cr.) | 0.05 (0.02–0.15) | 0.04 (0.02–0.14) | NS |
B2M (ng/ml) | 33.20 (12.85–142.67) | 65.08 (19.12–210.37) | NS |
B2M/cr. (ng/mg cr.) | 138.77 (12.14–331.83) | 116.77 (25.35–393.60) | NS |
GST-pi (ng/ml) | 1.76 (0.55–16.21) | 2.34 (0.63–9.09) | NS |
GST-pi/cr. (ng/mg cr.) | 4.80 (1.36–21.41) | 2.42 (0.74–8.51) | NS |
Clusterin (ng/ml) | 1.68 (0.93–5.61) | 3.17 (1.42–13.74) | NS |
Clusterin/cr. (ng/mg cr.) | 4.85 (1.58–13.03) | 4.17 (1.99–12.90) | NS |
Q1–Q3 – interquartile range; Cr – creatinine; – comparison of boys and girls; NS – non-significant; GST-pi – glutathione-S-transferase-pi; KIM-1 – kidney injury molecule-1; MCP-1 – monocyte chemoattractant protein-1; B2M – beta-2-microglobulin. |