Generation of a Predictive Clinical Model for Isolated Distal Deep Vein Thrombosis (ICMVT) Detection

31 December 2023: Clinical Research

Yan Xu ^1ABCDE , Mingmin Xu ^1CD , Xiaofang Zheng ^1CD , Fengxia Jin ^1BCD , Bin Meng ^1ABCDFG*

DOI: 10.12659/MSM.942840

Med Sci Monit 2023; 29:e942840

Table 2 Logistic regression analysis of risk factors for isolated calf muscle venous thrombosis.

Factor characteristics	Univariable analysis	Multivariable analysis	P value	OR	95% CI	P value
Factor characteristics	OR	95% CI	P value	OR	95% CI	P value
Age	2.39	1.73–3.29		1.98	1.21–3.25	0.007
Active cancer	1.19	0.63–2.23	0.59
CRP	6.99	4.18–11.71		3.25	1.08–9.79	0.037
Unilateral pitting oedema	13.68	4.76–39.34		3.52	1.67–7.4
D-dimer	4.1	2.95–5.68		2.42	1.22–4.82	0.011
Calf swelling >3 cm compared with asymptomatic side	7.74	3.76–15.95		2.68	1.37–5.25	0.004
FIB	2.19	1.48–3.26
Sex	1.91	1.23–2.97	0.004	2.24	1.44–3.51
LC	0.64	0.42–0.98	0.042
Recent immobilization >3 days or major surgery within the past 4 weeks	6.01	3.72–9.71		11.35	3.88–33.15
NP	1.58	1.01–2.48	0.046
NC	1.38	0.88–2.17	0.155
Localized tenderness of deep venous system	15.28	7.02–33.27		13.11	3.83–44.88
Paralysis, paresis, or recent plaster cast on lower extremities	3.79	2.39–6.02
PLT	0.92	0.55–1.52	0.735
PLTV	1.25	0.49–3.17	0.637
Entire leg swollen	9.45	4.47–19.97
WBC	1.26	0.73–1.97	0.475