Generation of a Predictive Clinical Model for Isolated Distal Deep Vein Thrombosis (ICMVT) Detection

31 December 2023 : Clinical Research

Yan Xu^1ABCDE, Mingmin Xu^1CD, Xiaofang Zheng^1CD, Fengxia Jin^1BCD, Bin Meng^1ABCDFG*

DOI: 10.12659/MSM.942840

Med Sci Monit 2023; 29:e942840

Background Material and Methods Results Discussion Conclusions References

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Table 2 Logistic regression analysis of risk factors for isolated calf muscle venous thrombosis.

Factor characteristics	Univariable analysis	Multivariable analysis	P value	OR	95% CI	P value
Factor characteristics	OR	95% CI	P value	OR	95% CI	P value
Age	2.39	1.73–3.29	<0.001	1.98	1.21–3.25	0.007
Active cancer	1.19	0.63–2.23	0.59
CRP	6.99	4.18–11.71	<0.001	3.25	1.08–9.79	0.037
Unilateral pitting oedema	13.68	4.76–39.34	<0.001	3.52	1.67–7.4	<0.001
D-dimer	4.1	2.95–5.68	<0.001	2.42	1.22–4.82	0.011
Calf swelling >3 cm compared with asymptomatic side	7.74	3.76–15.95	<0.001	2.68	1.37–5.25	0.004
FIB	2.19	1.48–3.26	<0.001
Sex	1.91	1.23–2.97	0.004	2.24	1.44–3.51	<0.001
LC	0.64	0.42–0.98	0.042
Recent immobilization >3 days or major surgery within the past 4 weeks	6.01	3.72–9.71	<0.001	11.35	3.88–33.15	<0.001
NP	1.58	1.01–2.48	0.046
NC	1.38	0.88–2.17	0.155
Localized tenderness of deep venous system	15.28	7.02–33.27	<0.001	13.11	3.83–44.88	<0.001
Paralysis, paresis, or recent plaster cast on lower extremities	3.79	2.39–6.02	<0.001
PLT	0.92	0.55–1.52	0.735
PLTV	1.25	0.49–3.17	0.637
Entire leg swollen	9.45	4.47–19.97	<0.001
WBC	1.26	0.73–1.97	0.475

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