03 February 2024 : Clinical Research
Impaired Capillary Recruitment Capacity in Obesity: A Subgroup Analysis of Prospective Observational Study on Anesthesia Effects
Soeun Jeon
1ABCDEG, Hyeon-Jeong Lee 23ABCDEF*, Hyun-Su Ri4BDE, Ah-Reum Cho 53ADF, Hyae-Jin Kim 53BDF, Jeong-Min Hong 53AF, Jiseok Baik 53DEF, Eun Ji Park 5ABC, Ohyun Kim 5DF, Jae-Han Kim 6EF
DOI: 10.12659/MSM.943036
Med Sci Monit 2024; 30:e943036
Table 2 Vital signs and microcirculatory parameters.
| Lean (BMI <25)(n=43) | Obese (BMI ≥25)(n=28) | P-value | |
|---|---|---|---|
| SpO (%) | 100.0 (99.0, 100.0) | 100.0 (98.3, 100.0) | 0.918a |
| Mean blood pressure (mmHg) | 92.2 (10.5) | 96.1 (10.4) | 0.127 |
| Heart rate (bpm) | 69.0 (63.0, 76.0) | 67.0 (59.3, 72.0) | 0.241a |
| EtCO (mmHg) | 35.5 (4.8) | 34.9 (4.0) | 0.567 |
| Skin temperature (°C) | 31.9 (2.1) | 31.8 (1.9) | 0.917 |
| StO, baseline (%) | 66.0 (55.0, 74.0) | 66.5 (58.3, 71.0) | 0.860a |
| StO, minimum (%) | 26.0 (15.0, 31.0) | 26.5 (15.0, 34.5) | 0.934a |
| StO, maximum (%) | 95.0 (88.0, 95.0) | 94.5 (92.3, 95.0) | 0.682a |
| Time to baseline StO (s) | 9.1 (7.8, 10.6) | 9.1 (7.3, 11.0) | 0.778a |
| ∇occl (%/s) | 0.222 (0.167, 0.256) | 0.222 (0.201, 0.249) | 0.659a |
| ∇recov (%/s) | 4.204 (3.339, 5.292) | 4.476 (3.568, 5.275) | 0.518a |
| SpO (%) | 100.0 (99.0, 100.0) | 100.0 (98.3, 100.0) | 0.182a |
| Mean blood pressure (mmHg) | 78.7 (11.1)* | 78.9 (10.8)* | 0.938 |
| Heart rate (bpm) | 80.0 (72.0, 92.0)* | 74.5 (66.3, 85.0)* | 0.168a |
| EtCO (mmHg) | 33.5 (2.8)* | 32.6 (2.6)* | 0.162 |
| Skin temperature (°C) | 32.5 (1.9)* | 32.5 (1.9)* | 0.872 |
| StO, baseline (%) | 71.0 (59.0, 77.0)* | 70.0 (67.0, 79.5)* | 0.343a |
| StO, minimum (%) | 35.0 (28.0, 45.0)* | 38.5 (24.3, 48.8)* | 0.625a |
| StO, maximum (%) | 95.0 (94.0, 95.0)* | 95.0 (95.0, 95.0)* | 0.441a |
| Time to baseline StO (s) | 8.4 (6.9, 9.7)* | 10.2 (8.3, 11.6) | 0.008a |
| ∇occl (%/s) | 0.194 (0.156, 0.217)* | 0.178 (0.144, 0.229)* | 0.791a |
| ∇recov (%/s) | 4.131 (3.491, 4.843) | 3.245 (2.737, 3.977)* | 0.003a |
| StO, baseline (%) | 9.2 (−3.4, 18.5) | 10.0 (3.0, 18.2) | 0.378a |
| StO, minimum (%) | 33.3 (7.4, 73.3) | 55.2 (16.6, 77.2) | 0.517a |
| StO, maximum (%) | 0.0 (0.0, 0.0) | 0.0 (0.0, 0.0) | 0.980a |
| Time to baseline StO (%) | −6.8 (−31.4, 11.0) | 8.6 (−12.0, 47.5) | 0.036a |
| ∇occl (%) | −12.5 (−24.4, 2.7) | −14.5 (−29.8, 3.4) | 0.359a |
| ∇recov (%) | 2.3 (−23.9, 35.1) | −24.4 (−34.0, −9.6) | 0.001a |
| SpO – pulse oximetry; EtCO – end-tidal carbon dioxide concentration; StO – tissue oxygen saturation; Tpre – before the induction of general anesthesia; Tpost – 30 min after the induction of general anesthesia; ∇occl – slope of StO descent to the lowest value during tourniquet inflation; ∇recov – slope from minimum to baseline StO during tourniquet deflation. a Mann-Whitney U test. * P | |||