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03 February 2024: Clinical Research

Impaired Capillary Recruitment Capacity in Obesity: A Subgroup Analysis of Prospective Observational Study on Anesthesia Effects

Soeun Jeon 1ABCDEG , Hyeon-Jeong Lee 23ABCDEF* , Hyun-Su Ri 4BDE , Ah-Reum Cho 23ADF , Hyae-Jin Kim 23BDF , Jeong-Min Hong 23AF , Jiseok Baik 23DEF , Eun Ji Park 2ABC , Ohyun Kim 2DF , Jae-Han Kim 5EF

DOI: 10.12659/MSM.943036

Med Sci Monit 2024; 30:e943036

Table 2 Vital signs and microcirculatory parameters.

Lean (BMI <25)(n=43)Obese (BMI ≥25)(n=28)P-value
SpO (%)100.0 (99.0, 100.0)100.0 (98.3, 100.0)0.918a
Mean blood pressure (mmHg)92.2 (10.5)96.1 (10.4)0.127
Heart rate (bpm)69.0 (63.0, 76.0)67.0 (59.3, 72.0)0.241a
EtCO (mmHg)35.5 (4.8)34.9 (4.0)0.567
Skin temperature (°C)31.9 (2.1)31.8 (1.9)0.917
StO, baseline (%)66.0 (55.0, 74.0)66.5 (58.3, 71.0)0.860a
StO, minimum (%)26.0 (15.0, 31.0)26.5 (15.0, 34.5)0.934a
StO, maximum (%)95.0 (88.0, 95.0)94.5 (92.3, 95.0)0.682a
Time to baseline StO (s)9.1 (7.8, 10.6)9.1 (7.3, 11.0)0.778a
∇occl (%/s)0.222 (0.167, 0.256)0.222 (0.201, 0.249)0.659a
∇recov (%/s)4.204 (3.339, 5.292)4.476 (3.568, 5.275)0.518a
SpO (%)100.0 (99.0, 100.0)100.0 (98.3, 100.0)0.182a
Mean blood pressure (mmHg)78.7 (11.1)* 78.9 (10.8)* 0.938
Heart rate (bpm)80.0 (72.0, 92.0)* 74.5 (66.3, 85.0)* 0.168a
EtCO (mmHg)33.5 (2.8)* 32.6 (2.6)* 0.162
Skin temperature (°C)32.5 (1.9)* 32.5 (1.9)* 0.872
StO, baseline (%)71.0 (59.0, 77.0)* 70.0 (67.0, 79.5)* 0.343a
StO, minimum (%)35.0 (28.0, 45.0)* 38.5 (24.3, 48.8)* 0.625a
StO, maximum (%)95.0 (94.0, 95.0)* 95.0 (95.0, 95.0)* 0.441a
Time to baseline StO (s)8.4 (6.9, 9.7)* 10.2 (8.3, 11.6)0.008a
∇occl (%/s)0.194 (0.156, 0.217)* 0.178 (0.144, 0.229)* 0.791a
∇recov (%/s)4.131 (3.491, 4.843)3.245 (2.737, 3.977)* 0.003a
StO, baseline (%)9.2 (−3.4, 18.5)10.0 (3.0, 18.2)0.378a
StO, minimum (%)33.3 (7.4, 73.3)55.2 (16.6, 77.2)0.517a
StO, maximum (%)0.0 (0.0, 0.0)0.0 (0.0, 0.0)0.980a
Time to baseline StO (%)−6.8 (−31.4, 11.0)8.6 (−12.0, 47.5)0.036a
∇occl (%)−12.5 (−24.4, 2.7)−14.5 (−29.8, 3.4)0.359a
∇recov (%)2.3 (−23.9, 35.1)−24.4 (−34.0, −9.6)0.001a
SpO – pulse oximetry; EtCO – end-tidal carbon dioxide concentration; StO – tissue oxygen saturation; Tpre – before the induction of general anesthesia; Tpost – 30 min after the induction of general anesthesia; ∇occl – slope of StO descent to the lowest value during tourniquet inflation; ∇recov – slope from minimum to baseline StO during tourniquet deflation.
a Mann-Whitney U test.
* P

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750