30 March 2024 : Clinical Research
Potential Value of HSP90α in Prognosis of Triple-Negative Breast Cancer
Han Fei Wang12CDEF, Ying Chen12G, Bang Cao3E, Jing Pei12A*DOI: 10.12659/MSM.943049
Med Sci Monit 2024; 30:e943049
Table 4 Cox multivariate survival analyses of 127 patients with TNBC.
| Multivariate analysis | Progression-free survival | Overall survival | ||
|---|---|---|---|---|
| HR (95% CI) | p Value | HR (95% CI) | p Value | |
| BMI | ||||
| ≥28 vs <28 | – | – | 2.072 (1.251, 3.429) | 0.005 |
| T | ||||
| 3, 4 vs 1, 2 | 0.998 (0.639, 1.558) | 0.992 | 1.751 (1.013, 3.028) | 0.045 |
| M | ||||
| 1 vs 0 | 2.348 (1.475, 3.738) | <0.001 | 1.448 (0.857, 2.447) | 0.166 |
| TNM | ||||
| I, II vs III, IV | 4.172 (1.789, 9.731) | 0.001 | 23.616 (3.047, 183.024) | 0.002 |
| Surgery | ||||
| Yes vs No | 0.843 (0.413, 1.723) | 0.640 | 0.113 (0.029, 0.439) | 0.002 |
| HSP90α | ||||
| ≥81.09 vs <81.09 | 2.020 (1.333, 3.059) | 0.001 | 3.772 (0.728, 19.540) | 0.014 |
| CA199 | ||||
| <40 vs ≥40 | 1.141 (0.739, 1.762) | 0.553 | 0.979 (0.603, 1.590) | 0.933 |