29 May 2024 : Database Analysis
Long-Term Prognosis of Patients Undergoing Percutaneous Coronary Intervention: The Impact of Serum Creatinine Levels on All-Cause Mortality
Chenghao Yang12ABCDEF, Lingxiao Zhang12CDE, Xinyue Ding1ABF, Zhang Hui1CD, Junqing Gao1AB, Zongjun Liu1ABG*DOI: 10.12659/MSM.943063
Med Sci Monit 2024; 30:e943063
Table 3 Relationship between sCr (μmol/L) and clinical events/all cause death in different models.
| Model IOR (95%CI) | P value | Model IIOR (95%CI) | P value | Model IIIOR (95%CI) | P value | |
|---|---|---|---|---|---|---|
| Log2 creatinine | 1.379 (1.066, 1.783) | 0.01431 | 1.211 (0.925, 1.585) | 0.16438 | 1.306 (0.902, 1.889) | 0.15719 |
| Creatinine quartile | ||||||
| Q1 (1.39–197.28) | Ref | Ref | Ref | |||
| Q2 (197.29–275.64) | 0.98 (0.67, 1.44) | 0.9348 | 0.98 (0.66, 1.44) | 0.9030 | 1.20 (0.69, 2.10) | 0.5219 |
| Q3 (275.65–354.00) | 1.12 (0.77, 1.62) | 0.5463 | 1.14 (0.76, 1.71) | 0.5188 | 1.70 (0.96, 3.01) | 0.0710 |
| Q4 (354.01–785.00) | 1.57 (1.11, 2.22) | 0.0105 | 1.36 (0.92, 2.00) | 0.1220 | 1.64 (0.93, 2.89) | 0.0865 |
| for trend | 0.006 | 0.077 | 0.064 | |||
| Log2 creatinine | 1.776 (1.300, 2.426) | 0.00031 | 1.570 (1.130, 2.182) | 0.00724 | 2.178 (1.317, 3.603) | 0.00243 |
| Creatinine quartile | ||||||
| Q1 (1.39–197.28) | Ref | Ref | Ref | |||
| Q2 (197.29–275.64) | 1.30 (0.80, 2.12) | 0.2846 | 1.34 (0.81, 2.21) | 0.2552 | 2.27 (1.01, 5.12) | 0.0477 |
| Q3 (275.65–354.00) | 1.21 (0.74, 1.97) | 0.4451 | 1.40 (0.82, 2.40) | 0.2132 | 3.02 (1.30, 7.05) | 0.0105 |
| Q4 (354.01–785.00) | 1.88 (1.20, 2.94) | 0.0061 | 1.66 (1.00, 2.76) | 0.0494 | 2.57 (1.12, 5.91) | 0.0259 |
| for trend | 0.009 | 0.058 | 0.041 | |||
| The 3 multiple linear regression models. we did not adjust for other covariants. we adjusted for sex and age. we adjusted for sex, age, systolic blood pressure, diastolic blood pressure, glucose, bilirubin, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, total cholesterol, number of diseased vessels, histories of heart failure, atrial fibrillation, hypertension, diabetes mellitus, chronic obstructive pulmonary disease (COPD), old myocardial infarction, stroke, peripheral vascular disease, previous percutaneous coronary intervention (PCI), previous coronary artery bypass graft (CABG), and third-degree atrioventricular block, smoking, type of stent, and use of aspirin, clopidogrel, angiotensin-converting enzyme inhibitors (ACEI), β-blockers, calcium channel blockers (CCB), and statins. | ||||||