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20 May 2024: Clinical Research

Diagnostic Efficiency of ACR-TIRADS Score for Differentiating Benign and Malignant Thyroid Nodules of Various Pathological Types

Yan Xu 1ABCDEF , Jiashun Pi 2CDEF , Yihan Jinghu 2BCDEF , Xiaotao Wang 1BCDE , Dong Xu 3AEG* , Jie Liu 45ABCDEFG*

DOI: 10.12659/MSM.943228

Med Sci Monit 2024; 30:e943228

Table 1 Comparison of general data and ultrasonic characteristics of benign and malignant thyroid nodules.

Malignant (n=829)Benign (n=846)P
Age (y)+46.83±13.26351.33±12.1610.000*
Max size (mm)14.67±13.85424.08±16.3810.000*
Female599 (72.3)636 (75.2)
Male230 (27.7)210 (24.8)
Left thyroid371 (44.8)402 (47.5)
Right thyroid418 (50.4)428 (50.6)
Thyroid isthmus40 (4.8)16 (1.9)
Cystic or almost completely cystic51 (6)
Spongiform54 (6.4)
Mixed cystic and solid20 (2.4)317 (37.4)
Solid or almost completely solid809 (97.4)424 (50.2)
Anechoic59 (7.0)
Hyperechoic or isoechoic15 (1.8)264 (31.2)
Hypoechoic772 (93.1)523 (61.8)
Very hypoechoic42 (5.1)
Wider-than-tall426 (51.4)47 (5.6)
Taller-than-wide403 (48.6)799 (94.4)
Smooth363 (43.8)794 (94)
Ill-defined128 (15.4)40 (4.6)
Lobulated or irregular282 (34)12 (1.4)
Extra-thyroidal extension56 (6.8)
Echogenic Foci0.000*
None or large comet-tail artifacts499 (60.2)732 (86.5)
Macrocalcifications57 (6.9)78 (9.2)
Peripheral (rim) calcifications55 (6.6)17 (2.0)
Punctate echogenic foci218 (26.3)19 (2.2)
Add Points for TI-RADS+7.35±2.1503.28±1.4770.000*
ACR TI-RADS risk level0.000*
TR151 (6.0)
TR2132 (15.6)
TR37 (0.8)368 (43.5)
TR4215 (25.9)260 (30.7)
TR5607 (73.2)35 (4.1)
Data are numbers of nodules, with percentages in parentheses. ACR – American College of Radiology; TIRADS – Thyroid Imaging Reporting and Data System; TR – TI-RADS risk level. Numbers in parentheses represent percentage within a given group (benign, malignant). Data are shown in means±standard deviation.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750