04 March 2024 : Clinical Research
Comparison of Modified Shock Index and Shock Index for Predicting Massive Transfusion in Women with Primary Postpartum Hemorrhage: A Retrospective Study
Hyojeong Kwon1CDEF, Chang Hwan Sohn1ABCDEF*, Sang-Min Kim1CDF, Youn-Jung Kim1DF, Seung Mok Ryoo1DF, Shin Ahn1DF, Dong-Woo Seo1DF, Won Young Kim1DFDOI: 10.12659/MSM.943286
Med Sci Monit 2024; 30:e943286
Table 2 A comparison of laboratory findings, blood transfusion amounts, and clinical outcomes based on massive transfusion in patients with primary postpartum hemorrhage.
| All patients (n=612) | MT group (n=105) | Non-MT group (n=507) | P value | |
|---|---|---|---|---|
| Laboratory findings | ||||
| White blood cell, ×10/μL | 17.2 (13.9–21.3) | 17.8 (12.5–22.5) | 17.1 (14.0–21.2) | 0.870 |
| Hemoglobin, g/dL | 9.8 (8.2–11.1) | 7.2 (5.6–9.8) | 10.1 (8.8–11.3) | <0.001 |
| 6Hematocrit, % | 29.7 (25.3–33.7) | 22.2 (17.6–29.2) | 30.6 (26.7–34.1) | <0.001 |
| Platelet, ×10/μL | 147.0 (114.0–186.0) | 114.0 (86.5–146.5) | 155.0 (121.0–191.0) | <0.001 |
| Prothrombin time, INR | 1.1 (1.0–1.3) | 1.6 (1.3–2.8) | 1.1 (1.0–1.2) | <0.001 |
| Blood urea nitrogen, mg/dL | 7.0 (6.0–10.0) | 9.0 (7.0–11.0) | 7.0 (6.0–9.0) | <0.001 |
| Creatinine, mg/dL | 0.6 (0.5–0.7) | 0.7 (0.6–0.9) | 0.6 (0.5–0.7) | <0.001 |
| C-reactive protein, mg/dL | 0.5 (0.2–0.9) | 0.4 (0.2–0.6) | 0.5 (0.2–1.0) | 0.007 |
| Amount of blood transfusion, units | ||||
| pRBCs within 24 hours | 3.0 (2.0–7.0) | 13.0 (11.0–20.0) | 3.0 (1.0–5.0) | <0.001 |
| Total pRBCs | 5.0 (2.0–10.0) | 16.0 (12.0–21.0) | 4.0 (2.0–7.0) | <0.001 |
| Total FFP | 3.0 (0.0–7.0) | 12.0 (7.5–15.0) | 2.0 (0.0–5.0) | <0.001 |
| Total PC | 0.0 (0.0–8.0) | 12.0 (8.0–20.0) | 0.0 (0.0–0.0) | <0.001 |
| Clinical outcome | ||||
| Embolization | 309 (50.5) | 92 (87.6) | 217 (42.8) | <0.001 |
| Hysterectomy | 6 (1.0) | 4 (3.8) | 2 (0.4) | 0.009 |
| Hospital LOS, days | 2.0 (1.0–4.0) | 5.0 (3.0–7.0) | 2.0 (1.0–3.0) | <0.001 |
| ICU admission | 51 (8.3) | 35 (33.3) | 16 (3.2) | <0.001 |
| In-hospital mortality | 5 (0.8) | 5 (4.8) | 0 (0.0) | <0.001 |
| All values are presented as the median (interquartile range) or as numbers (percentages). MT – massive transfusion; INR – international normalized ratio; pRBC – packed red blood cells; FFP – fresh frozen plasma; PC – platelet concentrate; LOS – length of stay; ICU – Intensive Care Unit. | ||||