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18 February 2024: Clinical Research

Vertical Relationship Ratio (VRR): A High Reliability and Accuracy Radiographic Measurement for Basilar Invagination in Rheumatoid Arthritis

Monchai Ruangchainikom 1ABDEF , Ekkapoj Korwutthikulrangsri 1E , Apisit Rattanatanasarn 1C , Ishthayapong Kanjanakeereewong 1C , Win Boonsirikamchai 2C , Panlop Tirawanish 3C , Surin Thanapipatsiri 1A , Werasak Sutipornpalangkul 1ADE*

DOI: 10.12659/MSM.943329

Med Sci Monit 2024; 30:e943329

Table 1 Demographic data and different measurement parameters in each group of patients.

Non-RA (n=56)RA with BI (n=28)RA without BI (n=37)P value
 Male23 (65.7%)10 (33.3%)* 6 (16.7%)** a
 Female12 (34.3%)20 (66.7%)30 (83.3%)
 Mean±SD39.80±14.5659.00±11.85* 57.06±15.61** b
 Median (range)42.00 (18–68)60.00 (39–89)58.00 (23–90)
 Vertical relationship ratio
  Median (range)2.12 (2.03–2.36)1.84 (1.17–2.16)* 2.24 (2.02–2.56)*** c
 Ranawat method (mm)
  Median (range)17.14 (14.36–23.26)11.81 (3.52–21.98)* 16.92 (10.33–20.81)***
 Modified Ranawat (mm)
  Mean±SD34.69±2.4627.68±4.78* 32.68±2.69,** b
  95% CI33.85–35.5425.90–29.4731.77–33.59
 Redlund-Johnell line (mm)
  Mean±SD41.91±5.7034.30±5.87* 39.30±5.67*** b
  95% CI39.95–43.8732.11–36.4937.38–41.21
Non-RA – non-rheumatoid arthritis patients, RA with BI – rheumatoid arthritis patients with basilar invagination, RA without BI – rheumatoid arthritis patients without basilar invagination.
* , , have value less than 0.05,
* Non-RA group vs RA with BI group,
** Non-RA group vs RA without BI group,
*** RA with BI vs RA without BI. Statistical analysis by
a chi-square test,
b One-way ANOVA,
c Kruskal-Wallis test.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750