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18 February 2024: Clinical Research

Vertical Relationship Ratio (VRR): A High Reliability and Accuracy Radiographic Measurement for Basilar Invagination in Rheumatoid Arthritis

Monchai Ruangchainikom 1ABDEF , Ekkapoj Korwutthikulrangsri 1E , Apisit Rattanatanasarn 1C , Ishthayapong Kanjanakeereewong 1C , Win Boonsirikamchai 2C , Panlop Tirawanish 3C , Surin Thanapipatsiri 1A , Werasak Sutipornpalangkul 1ADE*

DOI: 10.12659/MSM.943329

Med Sci Monit 2024; 30:e943329

Table 2 Intra- and inter-observer reliability of different measurements in each group of patients.

Intra-observer reliabilityInter-observer reliability
Rater 1Rater 2
Mean±SDICC (95% CI)Mean±SDICC (95% CI)
Median (range)Median (range)
Vertical relationship ratio
 Non-RA2.17±0.110.96 (0.91, 0.98)2.15±0.120.92 (0.84, 0.96)0.86 (0.75–0.93)
2.16 (2.03–2.37)2.11 (2.01–2.36)
 RA with BI1.78±0.220.97 (0.94, 0.99)1.80 ±0.240.96 (0.91, 0.98)0.97 (0.93, 0.98)
1.81 (1.16–2.16)1.84 (1.19–2.17)
 RA without BI2.20±0.110.98 (0.95, 0.99)2.23 ±0.140.91 (0.84,0.96)0.89 (0.80, 0.95)
2.22 (2.03–2.53)2.24 (2.01–2.59)
Ranawat method
 Non-RA17.57±1.630.60 (0.34, 0.78)17.61±2.350.68 (0.46–0.83)0.80 (0.63–0.89)
17.46 (14.85–20.69)17.32 (13.79–26.46)
 RA with BI12.35±3.980.89 (0.78, 0.95)11.97 ±4.090.96 (0.91, 0.98)0.91 (0.82, 0.96)
12.25 (4.30–20.59)11.69 (2.74–23.36)
 RA without BI16.57±2.060.88 (0.78, 0.94)16.51 ±2.050.80 (0.64, 0.89)0.92 (0.85, 0.96)
17.00 (10.32–20.16)16.95 (10.34–21.46)
Modified Ranawat method
 Non-RA35.37±2.590.79 (0.63, 0.89)34.37±2.510.78 (0.60, 0.88)0.86 (0.74, 0.93)
34.62 (30.68–41.39)34.03 (30.09–40.23)
 RA with BI27.87±4.820.98 (0.97, 0.99)27.50±4.790.97 (0.95, 0.99)0.98 (0.96, 0.99)
27.72 (18.17–38.94)26.90 (17.99–40.97)
 RA without BI32.86±2.770.97 (93, 0.98)32.50±2.650.97 (0.94, 0.99)0.96 (0.92, 0.98)
33.30 (26.59–40.41)33.03 (26.19–40.22)
Redlund-Johnell line
 Non-RA41.85±5.720.96 (0.93, 0.98)41.97±5.740.99 (0.98, 0.99)0.98 (0.96, 0.99)
41.72 (32.06–52.41)41.75 (32.67–53.64)
 RA with BI34.57±6.090.98 (0.96, 0.99)34.02±5.900.99 (0.99, 0.99)0.92 (0.84, 0.96)
35.31 (18.94–46.48)33.54 (20.17–45.47)
 RA without BI39.35 ±5.730.98 (0.96, 0.99)39.25 ±5.690.98 (0.96, 0.98)0.97 (0.94, 0.98)
40.17 (25.83–50.24)39.82 (28.22–49.51)
ICC – intraclass correlation coefficient; Non-RA – non-rheumatoid arthritis patients; RA with BI – Rheumatoid arthritis patients with basilar invagination; RA without BI – rheumatoid arthritis patients without basilar invagination. Statistical analysis by using intraclass coefficient (ICC) scores with 95% confidence intervals.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750