13 April 2024 : Clinical Research
Effect of Nasal Continuous Positive Airway Pressure on Retinopathy of Prematurity in Preterm Newborns: A Comparative Analysis with Mechanical Ventilation and High-Flow Nasal Cannula Therapy
Daniela M. Cioboata12ABDG, Aniko M. Manea12BDE*, Oana C. Costescu12AC, Florina M. Doandes12DF, Timea E. Brandibur12BF, Nicoleta Lungu12A, Mihai Dinu3C, Florina Stoica4A, Radu E. Iacob5B, Marioara Boia12ADEDOI: 10.12659/MSM.943486
Med Sci Monit 2024; 30:e943486
Table 2 Multivariate binary logistic regression analysis results showing the associations between different interventions or perinatal characteristics and ROP.
| Characteristics | AOR (95% CI) | P value |
|---|---|---|
| Sex, Male/Female | 2.646 (0.955–7.326) | 0.061 |
| GA | 1.169 (0.874–1.564) | 0.293 |
| BW | 0.998 (0.996–0.999) | <0.05 |
| Apgar score at 1 min | 0.775 (0.500–1.201) | 0.254 |
| Apgar score at 5 min | 0.782 (0.398–1.537) | 0.476 |
| Hb at 1 day of life | 0.764 (0.373–1.565) | 0.462 |
| HCT at 1 day of life | 1.017 (0.776–1.333) | 0.901 |
| RBC count at 1 day of life | 1.810 (0.354–9.264) | 0.476 |
| Transfusions, yes/no | 2.413 (0.874–6.667) | 0.089 |
| nCPAP therapy, yes/no | 7.264 (2.622–20.120) | <0.001 |
| ROP – retinopathy of prematurity; AOR – adjusted odds ratio; GA – gestational age; BW – birth weight; Hb – hemoglobin; HCT – hematocrit; RBC – red blood cell; nCPAP – nasal continuous positive airway pressure. | ||