06 May 2024 : Clinical Research
Tissue Inhibitors of Metalloproteinase 1 (TIMP-1) and 3 (TIMP-3) as New Markers of Acute Kidney Injury After Massive Burns
Wojciech Klimm



DOI: 10.12659/MSM.943500
Med Sci Monit 2024; 30:e943500
Table 1 Characteristics of the studied group of patients.
Characteristics | N=33 |
---|---|
Sex (M/F) | 22/11 |
Age (years), mean (±SD) | 48 (±18.58) |
BMI (kg/m), mean (±SD) | 25.77 (±5.42) |
TBSA (m), mean (±SD) | 1.89 (±0.25) |
Burned TBSA (%), mean (±SD) | 42.21 (±18.14) |
3 degree burns, n (%) | 22 (66.66) |
TBSA with 3 degree burns (m), mean(±SD) | 12.36 (±7.27) |
Respiratory tract burns, n (%) | 23 (69.7) |
Consciousness disturbances (GCS), n (%) | |
None or mild (13–15 pts) | 8 (24,24) |
Moderate (9–12 pts) | 0 |
Severe or intubation (<8 pts) | 25 (75,76) |
ABSI score (pts), mean (±SD) | 5.82 (±2.2) |
APACHE II score (pts), mean (±SD) | 15.27 (±8.13) |
Patients with AKI-positive status, n (%) | 15 (45.5) |
AKI-positive status in RIFLE classification | |
Risk, n (% active AKI-positive) | 14 (93.33) |
Injury, n (% AKI-positive) | 13 (86.67) |
Failure, n (% AKI-positive) | 10 (66.67) |
Requirement of renal replacement therapy, n (% AKI-positive) | 5 (33,33) |
Administration of pressor amines, n (%) | 22 (66.67) |
Death/survival, n (%) | 16 (48.48)/17 (51.52) |
SD – standard deviation; BMI – body mass index; TBSA – total body surface area; GCS – Glasgow coma scale; ABSI – Abbreviated Burn Severity Index; AKI – acute kidney injury; RIFLE – Risk, Injury, Failure, Loss-of-function, End-stage classification; n – number of patients. |