28 March 2024 : Clinical Research
Prognostic Significance of Neutrophil-to-Lymphocyte Ratio in Predicting Complete Pathological Response in Rectal Cancer Patients Receiving Neoadjuvant Chemoradiotherapy
Mustafa Karaca
1ACDEF, Ece Salim2ABDEF, Mustafa Serkan Alemdar 3BDEF, Özge Deniz Karaca 2BEF, Mustafa Özgür Arıcı 3BDEF*
DOI: 10.12659/MSM.943750
Med Sci Monit 2024; 30:e943750
Table 1 Demographic and clinical characteristics of the patients.
| Variables | Total patients (n=187) |
|---|---|
| Age (years), mean±SD | 64.59±11.19 |
| Gender, n (%) | |
| Male | 123 (65.8) |
| Female | 64 (34.2) |
| Comorbid disease, n (%) | 75 (40.1) |
| Diabetes mellitus | 37 (19.8) |
| Hypertension | 34 (18.2) |
| Ulcerative colitis | 2 (1.1) |
| Coronary artery disease | 2 (1.1) |
| Chemotherapy agent, n (%) | |
| Capecitabine | 96 (51.3) |
| 5-FU | 91 (48.7) |
| Type of surgery, n (%) | |
| LAR | 154 (82.4) |
| MILES operation | 33 (17.6) |
| Pathological response, n (%) | |
| Complete response | 34 (18.2) |
| Near-complete response | 61 (32.6) |
| Partial response | 68 (36.4) |
| No response | 24 (12.8) |
| 5-FU – 5-Fluorouracil; LAR – low anterior resection. | |