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28 March 2024: Clinical Research

Prognostic Significance of Neutrophil-to-Lymphocyte Ratio in Predicting Complete Pathological Response in Rectal Cancer Patients Receiving Neoadjuvant Chemoradiotherapy

Mustafa Karaca 1ACDEF* , Ece Salim 2ABDEF , Mustafa Serkan Alemdar 3BDEF , Özge Deniz Karaca 2BEF , Mustafa Özgür Arıcı 3BDEF

DOI: 10.12659/MSM.943750

Med Sci Monit 2024; 30:e943750

Table 1 Demographic and clinical characteristics of the patients.

VariablesTotal patients (n=187)
Age (years), mean±SD64.59±11.19
Gender, n (%)
 Male123 (65.8)
 Female64 (34.2)
Comorbid disease, n (%)75 (40.1)
 Diabetes mellitus37 (19.8)
 Hypertension34 (18.2)
 Ulcerative colitis2 (1.1)
 Coronary artery disease2 (1.1)
Chemotherapy agent, n (%)
 Capecitabine96 (51.3)
 5-FU91 (48.7)
Type of surgery, n (%)
 LAR154 (82.4)
 MILES operation33 (17.6)
Pathological response, n (%)
 Complete response34 (18.2)
 Near-complete response61 (32.6)
 Partial response68 (36.4)
 No response24 (12.8)
5-FU – 5-Fluorouracil; LAR – low anterior resection.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750