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28 March 2024: Clinical Research

Prognostic Significance of Neutrophil-to-Lymphocyte Ratio in Predicting Complete Pathological Response in Rectal Cancer Patients Receiving Neoadjuvant Chemoradiotherapy

Mustafa Karaca 1ACDEF* , Ece Salim 2ABDEF , Mustafa Serkan Alemdar 3BDEF , Özge Deniz Karaca 2BEF , Mustafa Özgür Arıcı 3BDEF

DOI: 10.12659/MSM.943750

Med Sci Monit 2024; 30:e943750

Table 6 Factors associated with progression-free survival of patients.

HR (95% CI)pHR (95% CI)p
Age1.022 (0.999–1.045) (0.998–1.043)0.074
Male gender1.755 (1.027–3)1.693 (0.976–2.937)0.061
Comorbid disease0.748 (0.454–1.231)0.253
Chemotherapy agent
 5-FU1.981 (1.221–3.215)1.941 (1.165–3.234)
Type of surgery
 MILES operation1.318 (0.755–2.301)0.332
Hemoglobin at diagnosis0.972 (0.865–1.091)0.626
Platelets at diagnosis1.001 (0.998–1.004)0.489
LDH at diagnosis1.003 (0.998–1.007)0.228
NLR at diagnosis >3.631.911 (1.187–3.077)1.314 (0.784–2.204)0.300
HR – hazard ratio; CI – confidence interval; 5-FU – 5-Fluorouracil; LAR – low anterior resection; LDH – lactate dehydrogenase; NLR – neutrophil/lymphocyte ratio.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750