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28 January 2024: Review Articles

A Review of IgA Vasculitis (Henoch-Schönlein Purpura) Past, Present, and Future

Dinah V. Parums CDEF*

DOI: 10.12659/MSM.943912

Med Sci Monit 2024; 30:e943912

Table 2 Differential diagnoses of small vessel vasculitis [47,48].

Symptom/signDifferential diagnoses
Petechiae and purpuric skin rashesImmune thrombocytopenia (ITP)Hemolytic uremic syndrome (HUS)Drug reactionLeukemiaCoagulopathiesAnticoagulation therapy
Leukocytoclastic vasculitisAcute hemorrhagic edema of infancy (AHEI) (also known as Finkelstein or Seidlmayer disease)Hypersensitivity vasculitisGranulomatosis with polyangiitis (Wegener’s)Microscopic polyangiitisEosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)Vasculitis secondary to connective tissue disease, including systemic lupus erythematosus [SLE)Vasculitis secondary to infectious disease (hepatitis B and hepatitis C)
NB. Laboratory tests for autoantibodies, including antinuclear antibodies, anti-double-stranded DNA (anti-dsDNA), and antineutrophil cytoplasmic antibodies (ANCA), are usually negative in IgA vasculitis.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750