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09 May 2024 : Clinical Research  

Renal Dysfunction Increases Risk of Adverse Cardiovascular Events in 5-Year Follow-Up Study of Intermediate Coronary Artery Lesions

Piotr Baruś ORCID logo1ABCDEF, Jaromir Hunia ORCID logo1ACDEF, Rafał Kaczorowski ORCID logo1ACDEF, Adrian Bednarek ORCID logo1ACDEF, Dorota Ochijewicz ORCID logo1ACEF, Karolina Gumiężna ORCID logo1ACEF, Łukasz Kołtowski ORCID logo1ACEF, Janusz Kochman ORCID logo1ADE, Marcin Grabowski ORCID logo1ADE, Mariusz Tomaniak ORCID logo1ABCDEF*

DOI: 10.12659/MSM.943956

Med Sci Monit 2024; 30:e943956

Table 1 Baseline characteristics.

All patients (n=100)Renal dysfunction patients (n=23)No renal dysfunction patients (n=77)p-value
Age – mean [years]64.6±9.767.7±8.163.6±9.70.044
Sex – women [n, %]22 (22.0%)5 (21.7%)17 (22.1%)0.097
AF15 (15.0%)5 (21.7%)10 (13.0%)0.315
HT83 (83.0%)21 (91.3%)62 (80.5%)0.227
Hypercholesterolemia65 (65.0%)12 (52.2%)53 (68.8%)0.142
DM32 (32.0%)7 (30.4%)25 (32.5%)0.854
DM (insulin)8 (8.0%)0 (0%)8 (10.4%)0.105
PAD10 (10.0%)2 (8.7%)8 (10.4%)0.812
Prior MI54 (54.0%)12 (52.2%)42 (54,5%)0.841
HF15 (15.0%)2 (8.7%)13 (16.9%)0.335
Previous stroke or TIA3 (3.0%)1 (4.3%)2 (2.6%)0.674
Active smokers18 (18.0%)1 (4.3%)17 (22.1%)0.050
Family history of CAD7 (7.0%)1 (4.3%)6 (7.8%)0.570
Prior CABG4 (4.0%)0 (0%)4 (5.2%)0.265
β-blockers95 (95.0%)20 (87.0%)75 (97.4%)0.044
Calcium channel blockers26 (26.0%)7 (30.4%)19 (24.7%)0.604
Angiotensin-converting-enzyme inhibitors67 (67.0%)13 (56.5%)54 (70.1%)0.223
Angiotensin receptor blockers21 (21.0%)7 (30.4%)14 (18.2%)0.399
Aspirin97 (97.0%)21 (91.3%)76 (98.7%)0.068
Clopidogrel64 (64.0%)17 (73.9%)47 (61.0%)0.259
Statin96 (96.0%)23 (100%)73 (94.8%)0.265
Nitrates3 (3.0%)1 (4.3%)2 (2.6%)0.666
Mineralocorticoid receptor antagonists8 (8.0%)0 (0%)8 (10.4%)0.228
Hemoglobin [g/dl]13.7 (13.0–14.8)13.7±1.413.7 (13.3–14.1)0.830
Hematocrit [%]40.3 (37.8–43.1)40.0±3.540.5 (39.4–41.5)0.609
Platelet Count [×10/l]224.2 (179.0–245.0)209.4±54.4226.4 (209.5–243.3)0.331
Na [mmol/l]141.1±2.8141.5±2.7140.9 (140.3–141.5)0.335
K [mmol/l]4.47±0.404.48±0.344.46±0.430.866
Creatinine [mg/dl]0.97±0.221.25±0.160.89±0.16<0.001
AF – atrial fibrillation; HT – hypertension; DM – diabetes mellitus; PAD – peripheral artery disease; MI – myocardial infarction; HF – heart failure; TIA – transient ischemic attack; CAD – coronary artery disease; CABG – coronary artery bypass grafting; Na – sodium; K – potassium. Data are presented as count (%), mean and standard deviation (±) or median and interquartile range (IQR).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750