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10 October 2024 : Review article  

Comprehensive Analysis of UBE-Related Complications: Prevention and Management Strategies from 4685 Patients

Lili Yang1AE, Tong Yu1ABC, Jianhang Jiao1BF, Tingting Hou1FG, Yang Wang1BF, Bin Zhao1CD, Minfei Wu1CE, Weibo Jiang1AEF*

DOI: 10.12659/MSM.944018

Med Sci Monit 2024; 30:e944018

Table 2 The types, causes, and treatment options of UBE complications reported in the literature.

Complications typesReferencesMorbidity (%)CausesTreatment options
Incidental dural tear[]20 2/65 (3.1)NRConservative management
Incidental dural tear[]10 3/72 (4.2)NR3 patients were observed with a dural tear in the ULIF group; the tear was covered with a dural patch instead of a primary repair
Incidental dural tear[]28 7/67 (13.2)NRFibrin seal patch, conversion to microscopic surgery, revision for duroplasty
Incidental dural tear[]23 18/797 (2.3)NRReoperation in 3, conserve treatment in 15
Incidental dural tear[]29 5/5 (100)NRNonpenetrating titanium vascular anastomosis clips
Incidental dural tear[]25 12/165 (7.27)Incidental thecal sac lesion during durotomyBed rest in 5fibrin sealant in 5the endoscopic suture in 2
Incidental dural tear[]26 25/1511 (1.6)Injury of central dural folding during flavectomy under turbid surgical fields due to small bleeds under water.Gelform, fibrin glue, open repair, TachoSil, blood patch, endoscopic clipping, or observation
Incidental dural tear[]30 2/29 (7)NRNR
Incidental dural tear[]27 29/643 (4.5)NR12 were treated with in hospital monitoring and bed rest14 were treated with a fibrin sealant2 were treated with a nonpenetrating titanium clip1 was converted to microscopic surgery
Incidental dural tear[]23 18/797 (2.3)NRReoperation in 3, conserve treatment in 15
Incidental dural tear[]31 2/21 (9.5)NRConservative treatment
Incidental dural tear[]3 1/106 (0.9)NRWithout open repair
Incidental dural tear[]9 2/42 (4.8)NRTachoSil (Nycomed, Linz, Austria)
Incidental dural tear[]32 2/105 (1.9)NRConservative treatment
Incidental dural tear[]33 3/71 (4.2)NRFibrin collagen patch (TachoComb) combined with lumbar drain for 5 to 7 days
Incidental dural tear[]15 3/43 (7)NRThe external pressure applied by the pump irrigation acted as a tamponade against CSF leak; the tear was sealed within 5 min with a small bleb.
Incidental dural tear[]34 2/55 (3.6)NRBed rest
Pseudomeningocele[]35 1/1 (100)Dural tear occurred during the laminotomy procedure using an osteotomeFibrin sealant patch was used to cover the dural tear via UBE
Incidental dural tear[]41 1/14 (7.1)NRConservative treatment
Foot drop[]28 1/67 (1.5)Dural tearReoperation
L5 root palsy[]41 1/14 (7.1)NRFollow up treatment in the outpatient clinic
Numbness of the contralateral leg[]51 2/11 (18.2)Incomplete removal of the ruptured disc on the contralateral sideNR
Incomplete decompression[]23 18/797 (2.3)Experience factorsConservative treatment (including medication and epidural steroid injection)
Incomplete decompression[]3 1/106 (0.9)NRReoperation
Incomplete decompression[]49 3/60 (5)The ruptured disc fragment was incompletely removedConversion to OLM
Headache[]34 2/55 (3.6)NRBed rest
Headache[]28 1/67 (1.5)Dural tear, CSF leakReoperation
Epidural hematoma[]44 94/310 (30.3)NRConservative treatment or reoperation
Epidural hematoma[]33 1/71 (1.4)NRNR
Epidural hematoma[]47 43/206 (20.9)NRGelatin-thrombin matrix sealant
Epidural hematoma[]32 1/105 (1)NRReoperation
Epidural hematoma[]20 3/65 (4.6)NRConservative management
Epidural hematoma[]23 18/797 (2.3)Experience factorsNR
Symptomatic hematoma[]30 1/29 (3)NRReoperation
Epidural hematoma and neurological symptoms[]34 1/55 (1.8)NRHematoma evacuation was performed using the UBE technique
Anemia[]61 42/136Hidden blood lossAdequate assessment of risk factors for hidden blood loss in the perioperative period. For details of risk factors, please see reference []61
Hydroperitoneum[]23 4/797 (0.5)NRExtended in-hospital monitoring and intermittent fluid drainage
Hydroperitoneum[]57 1/44 (2.3)If orientation were lost without scoping upward from the L5 transverse process and going straight down under the level of the L5 transverse process, the psoas muscle layer could be penetrated and infused saline could make hydroperitoneumSono-guided paracentesis was performed to treat and aspirated the infused saline
Back pain[]15 1/43 (2.3)Poor patient selectionPosterior instrumentation and fusion
Delayed wound healing[]3 2/106 (1.8)NRDebridement
Infection[]23 1/797 (0.1)NRRemove the infected abscess by UBE, 3 weeks of hospitalization for the administration of intravenous antibiotics, and 3 weeks of oral antibiotics
Infection[]33 1/71 (1.4)NRNR
Recurrent disc herniation[]15 1/43 (2.3)NRRe-surgery by UBE
Recurrent disc herniation[]5 1/31 (3.2)Spondylolytic spondylolisthesis preoperativelyTransforaminal interbody fusion via the UBE technique
Recurrent disc herniation[]23 18/797 (2.3)Incomplete decompressionNR
Restenosis[]31 1/21 (5)The worsening of the preoperatively known spondylolisthesis (2 mm)NR
Reoperation[]25 7/165 (4.24)NRNR
Reoperation[]23 35/797 (4.4)Hematoma, incidental dural tear, instability, infection, recurrence, incomplete operationDecompression or fusion
Reoperation[]28 1/67 (1.5)Dural tear, headache, CSF leak, foot dropAfter the failure of the fibrin seal patch and lumbar drain, revision for duroplasty was carried out
Reoperation[]32 1/105 (1)Epidural hematomaUBE decompression
Reoperation[]44 6/310 (1.9)Cauda equina syndrome or severe radiating pain after surgerySymptomatic epidural hematoma evacuation
Instability[]23 5/797 (0.6)NRAdditional fusion surgery in 2, conservative treatment in 3
UBE – unilateral biportal endoscopic; NR – not reported; OLM – open lumbar microdiscectomy; CSF – cerebrospinal fluid.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750