Effect of Individualized PEEP Guided by Driving Pressure on Diaphragm Function in Patients Undergoing Laparoscopic Radical Resection of Colorectal Cancer: A Randomized Controlled Trial

20 May 2024 : Clinical Research

Mingyue Zhang^1ABCF, Yongbo Yu^1BCD, Cheng Qiu^1CE, Xiaoqiong Xia^1BCD*, Yuanming Sun^1E, Liang Wang^1DE, Guifen Ma^1BE, Xiang Gao^1E

DOI: 10.12659/MSM.944022

Med Sci Monit 2024; 30:e944022

Introduction Material and Methods Results Discussion Conclusions References

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Table 1 Comparison of basic characteristics of patients in the 3 groups.

Parameter	C group (n=30)	F group (n=30)	I group (n=30)	F/χ2	P value
Sex (M/F)^b	18/12	20/10	19/11	0.287	0.866
Age (years) (mean±SD)^a	71.1±3.9	70.4±3.1	71.4±4.4	0.609	0.546
BMI(kg/m) (mean±SD)^a	24.8±2.2	23.7±1.7	24.1±2.0	2.527	0.086
ASA grade I/II (n)^b	10/20	9/21	12/18	0.689	0.709
Colorectal cancer site^b	10/20	8/22	9/21	0.317	0.853
FEV1/FVC(%) (mean±SD)^a	81.0±2.7	82.5±2.6	82.0±2.8	2.517	0.087
TOF ratio (mean±SD)^a	92.0±1.2	92.4±1.5	92.2±1.4	0.666	0.516
Operative time (mean±SD)^a	223.0±24.7	222.2±25.0	230.7±25.9	1.038	0.359
BMI – body mass index; ASA – American Society of Anesthesiologists; TOF – train-of-four (degree of neuromuscular blockage). ^a Single-factor ANOVA test; ^b χ tests.

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