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20 May 2024 : Clinical Research  

Effect of Individualized PEEP Guided by Driving Pressure on Diaphragm Function in Patients Undergoing Laparoscopic Radical Resection of Colorectal Cancer: A Randomized Controlled Trial

Mingyue Zhang1ABCF, Yongbo Yu1BCD, Cheng Qiu1CE, Xiaoqiong Xia1BCD*, Yuanming Sun1E, Liang Wang1DE, Guifen Ma1BE, Xiang Gao1E

DOI: 10.12659/MSM.944022

Med Sci Monit 2024; 30:e944022

Table 1 Comparison of basic characteristics of patients in the 3 groups.

ParameterC group (n=30)F group (n=30)I group (n=30)F/χ2P value
Sex (M/F)b 18/1220/1019/110.2870.866
Age (years) (mean±SD)a 71.1±3.970.4±3.171.4±4.40.6090.546
BMI(kg/m) (mean±SD)a 24.8±2.223.7±1.724.1±2.02.5270.086
ASA grade I/II (n)b 10/209/2112/180.6890.709
Colorectal cancer siteb 10/208/229/210.3170.853
FEV1/FVC(%) (mean±SD)a 81.0±2.782.5±2.682.0±2.82.5170.087
TOF ratio (mean±SD)a 92.0±1.292.4±1.592.2±1.40.6660.516
Operative time (mean±SD)a 223.0±24.7222.2±25.0230.7±25.91.0380.359
BMI – body mass index; ASA – American Society of Anesthesiologists; TOF – train-of-four (degree of neuromuscular blockage).
a Single-factor ANOVA test;
b χ tests.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750