22 May 2024 : Clinical Research
Incidence, Risk Factors, and Outcomes of Left Atrial Enlargement in Patients Requiring Right Ventricular Pacing: A Retrospective Study of 461 Cases from 2012 to 2020
Wei-Chieh Lee
123ABCDEF*, Wei-Ting Chang123CD, Hsiu-Yu Fang45B, Huang-Chung Chen 4B, Mien-Cheng Chen4EF, Ping-Yen Liu16EF
DOI: 10.12659/MSM.944114
Med Sci Monit 2024; 30:e944114
Table 2 Baseline and follow-up echocardiographic parameters between patients without and with significant LAE.
| Without significant LAE | With significant LAE | P value | |
|---|---|---|---|
| 365 | 96 | ||
| LA dimension (mm) | 35.2±3.7 | 31.1±4.5 | <0.001 |
| LVEF (%) | 69.5±8.4 | 69.1±10.1 | 0.715 |
| LVESV (mL) | 32.6±15.2 | 29.4±13.5 | 0.064 |
| LVEDV (mL) | 107.7±32.7 | 99.1±33.0 | 0.022 |
| MR grade | |||
| No or trivial MR (%) | 159 (43.6) | 49 (51.0) | 0.206 |
| Mild MR (%) | 206 (56.4) | 47 (49.0) | 0.206 |
| LA dimension (mm) | 35.6±5.0 | 41.8±5.8 | <0.001 |
| LVEF (%) | 61.4±13.4 | 57.9±12.8 | 0.022 |
| PICM (EF ≤50%) (%) | 73 (20.0) | 23 (24.0) | 0.399 |
| LVESV (mL) | 48.3±15.1 | 49.4±19.6 | 0.620 |
| LVEDV (mL) | 116.0±43.4 | 113.5±40.6 | 0.774 |
| MR grade | |||
| No and trivial (%) | 118 (32.6) | 19 (19.8) | 0.015 |
| Mild (%) | 211 (57.8) | 56 (58.3) | 0.926 |
| Moderate to severe (%) | 36 (9.9) | 21 (21.9) | 0.003 |
| 3.0 (2.6–3.3) | 4.3 (3.3–5.7) | 0.002 | |
| 1.0 (0–1.7) | 10.0 (9.0–11.0) | <0.001 | |
| 2.7 (0–4.9) | 32.3 (30.0–35.5) | <0.001 | |
| 0.2 (0–0.4) | 2.3 (1.9–3.0) | <0.001 | |
| ≥ | 181 (49.6) | 60 (62.5) | 0.029 |
| Data are expressed as mean (standard deviation) or median (interquartile range) or as number (percentage). LAE – left atrial enlargement; LVEF – left ventricular ejection fraction; LVESV – left ventricular end systolic volume; LVEDV – left ventricular end diastolic volume; MR – mitral regurgitation; PICM – pacing-induced cardiomyopathy. | |||