Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

22 May 2024: Clinical Research

Incidence, Risk Factors, and Outcomes of Left Atrial Enlargement in Patients Requiring Right Ventricular Pacing: A Retrospective Study of 461 Cases from 2012 to 2020

Wei-Chieh Lee 123ABCDEF , Wei-Ting Chang 123CD , Hsiu-Yu Fang 45B , Huang-Chung Chen 4B , Mien-Cheng Chen 4EF* , Ping-Yen Liu 16EF*

DOI: 10.12659/MSM.944114

Med Sci Monit 2024; 30:e944114

Table 3 Univariate and multivariate logistic regression analyses of predictors of significant LAE.

VariablesUnivariate analysisMultivariate analysis
OR95% CIP valueOR95% CIP value
Age (per 10 years)0.9410.793–1.1160.486
Diabetes mellitus0.7660.476–1.2350.275
Coronary artery disease0.8030.429–1.5040.493
End stage renal disease1.0590.383–2.9300.912
Prior stroke or TIA1.2840.683–2.4150.438
Pre-implant LA0.7920.746–0.8400.7760.728–0.828
Pre-implant LVEF0.9950.970–1.0210.714
Pre-implant LVEDV0.9910.983–0.9990.0210.9970.985–1.0100.676
Pre-implant LVESV0.9820.964–1.0010.0600.9920.963–1.0210.580
Post-implant LVEF0.9810.965–1.0070.0230.9760.957–0.9950.014
Post-implant LVEDV0.9970.993–1.0040.620
Post-implant LVESV1.0010.994–1.0070.773
Post-implant development of moderate to severe MR2.5591.413–4.6340.0022.3571.172–4.7400.016
Pacing QRS duration0.9940.979–1.0080.375
Lead position at lower septum and apex1.3380.760–2.3540.313
Pacing years (per year)1.0881.030–1.1490.003
≥3.3 years1.6941.068–2.6870.0251.5761.039–2.6460.045
New-onset atrial fibrillation after implantation1.4840.913–2.4110.1111.0890.489–2.4260.835
OR – odds ratio; CI – confidence interval; BMI – body mass index; TIA – transient ischemic attack; LA – left atrium; LAE – left atrial enlargement; LVEF – left ventricular ejection fraction; LVEDV – left ventricular end-diastolic volume; LVESV – left ventricular end-systolic volume; LVEF – left ventricular ejection fraction; PICM – pacing-induced cardiomyopathy; MR – mitral regurgitation; ACEI – angiotensin-converting-enzyme inhibitor; ARB – angiotensin II receptor blocker.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750