01 June 2024 : Clinical Research
Comparison of Fentanyl, Ketamine, and Lidocaine Combined with Propofol Anesthesia in Patients with Crohn Disease Undergoing Colonoscopy
Kamil Chudziński
1ABCDEF, Konstanty Szułdrzyński 1DEF, Miłosz Jankowski 1CDEF, Kamil Adamczyk 1EF*, Elżbieta Sokół-Kobielska2DEF
DOI: 10.12659/MSM.944116
Med Sci Monit 2024; 30:e944116
Table 5 Logistic regression models explaining the occurrence of desaturation.
| Desaturation | Logistic regression models | ||||
|---|---|---|---|---|---|
| No | Yes | Univariate | Multivariate | ||
| Age (years) | 41.1 (13.9) | 48.7 (14.6) | 1.04 (1.01–1.07; =) | – | |
| Sex | Male | 59 (80.8) | 14 (19.2) | – | – |
| Female | 60 (82.2) | 13 (17.8) | 0.91 (0.39–2.11; =0.831) | – | |
| Body mass index (kg/m) | 24.0 (4.3) | 26.2 (5.2) | 1.10 (1.01–1.20; =) | 1.20 (1.07–1.36; =) | |
| Analgesia group | fentanyl | 27 (57.4) | 20 (42.6) | – | – |
| ketamine | 44 (93.6) | 3 (6.4) | 0.09 (0.02–0.30; <) | 0.05 (0.01–0.18; <) | |
| lidocaine | 48 (92.3) | 4 (7.7) | 0.11 (0.03–0.33; <) | 0.05 (0.01–0.18; <) | |
| Colonoscopy duration (min) | 17.6 (9.1) | 1.05 (1.00–1.11; =0.059) | 1.08 (1.01–1.16; =) | ||
| Propofol dose (mg) | 14.7 (6.4) | 141.9 (49.8) | 1.01 (1.00–1.02; =) | – | |
| Propofol (mg/kg BW/min) | 116.6 (50.3) | 0.1 (0.1) | 0.96 (0.00–7532.47; =0.993) | ||
| For quantitative variables, the mean (SD) was reported. For qualitative variables, the number of patients (percentage) was reported. The results of the univariate and multivariate analysis were reported as odds ratio (95% CI). | |||||