02 August 2024 : Clinical Research
Transradial and Transfemoral Approaches for Vertebral Artery Stenting: A Single-Center, Prospective, Non-Inferiority Comparison
Yi Lv12BC, Changyang Zhong3ABDG*, Cong Wu1CD, Chunli Wu3ABF, Yuan Liu4CDDOI: 10.12659/MSM.944183
Med Sci Monit 2024; 30:e944183
Table 4 Primary and secondary outcomes.
| Outcomes | TFA (n=53) | Ipsilateral TRA (n=41) | Contralateral TRA (n=8) | P value |
|---|---|---|---|---|
| Primary outcomes | ||||
| Proportion of altered pathways during surgerya | 2 (3.64) | 0 (0) | 1 (11.1) | 0.184 |
| Success rate of stent | 51 (96.2) | 40 (97.6) | 8 (100) | 1 |
| Time from sheath placement to stent placement(min) median (IQR) | 29 (21,35.5) | 19 (12,24.5) | 20.5 (13.25,39.5) | |
| Discharge time(d) median (IQR) | 6 (5,7) | 4 (3,5) | 3.5 (2.25,4) | |
| Secondary outcomes | ||||
| Relevant score after operation, median (IQR) | ||||
| mRS score after operation | 0 (0,0) | 0 (0,0) | 0 (0,0.75) | 0.941 |
| NIHSS score after operation | 0 (0,1.5) | 1 (0,2) | 1 (0,2) | 0.453 |
| TIA within 30 days | 4 (7.5) | 3 (7.3) | 1 (12.5) | 0.725 |
| Vertebral artery restenosis occurred 6 months laterb | 8 (15.1) | 6 (14.6) | 1 (12.5) | 0.981 |
| 1 year follow-upc | ||||
| mRS score after-one year, median (IQR) | 0 (0,0) | 0 (0,0) | 0 (0,0) | 0.878 |
| NIHSS score after-one year, median (IQR) | 0 (0,1) | 0 (0,1) | 0.5 (0,1) | 0.375 |
| Symptomatic ISR within 1 year | 2 (3.8) | 3 (7.3) | 0 (0) | 0.769 |
| 1 year target vessel area of ischemic stroke | 2 (3.8) | 2 (4.9) | 0 (0) | 1 |
| Intracranial hemorrhage within 1 year | 1 (1.9) | 1 (2.4) | 0 (0) | 1 |
| Death within 1 year | 1 (1.9) | 1 (2.4) | 0 (0) | 1 |
| a Denominator prior to surgery. The TFA group featured 55 patients, the ipsilateral TRA group featured 38 patients, and the contralateral TRA group featured 9 patients; b TFA group; 4 patients were lost to follow-up and 2 patients declined examination. In the ipsilateral TRA group, 3 patients were lost to follow-up and 2 patients refused examination. One patient in the contralateral TRA group declined examination; c TRA group; 5 patients were lost to follow-up and 2 patients refused examination. Three of the follow-ups in the ipsilateral TRA group resulted in refusal to be examined. | ||||