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05 June 2024: Clinical Research

Serum Lipoprotein(a) Levels as a Predictor of Aortic Stiffness in Patients on Long-Term Peritoneal Dialysis

Po-Yu Huang 12BCDEF* , Bang-Gee Hsu 234ABCDEFG* , Yu-Li Lin 234ABCG , Chi-Chong Tang 23B , Hung-Hsiang Liou 5AD , Jen-Pi Tsai 124ABCDFG*

DOI: 10.12659/MSM.944348

Med Sci Monit 2024; 30:e944348

Table 4 The correlation between log-transformed lipoprotein(a) level and clinical variables among 148 patients on peritoneal dialysis therapy.

VariablesSpearman’s correlation coefficientP value
Diabetes mellitus−0.0520.530
Age (years)0.1270.125
Log-PD vintage (months)−0.0650.434
Body mass index (kg/m)0.1010.221
Waist circumference (cm)0.1000.225
SBP (mmHg)0.1600.052
DBP (mmHg)0.0700.399
Hemoglobin (g/dL)−0.0870.293
Total cholesterol (mg/dL)0.321*
Log-Triglyceride (mg/dL)0.1270.125
Log-Glucose (mg/dL)−0.0350.671
Albumin (g/dL)−0.1940.018*
BUN (mg/dL)0.2340.004*
Creatinine (mg/dL)0.0470.573
Total calcium (mg/dL)0.0610.460
Phosphorus (mg/dL)0.0980.238
Log-iPTH (pg/mL)0.1330.106
Weekly Kt/V−0.1060.201
Peritoneal Kt/V−0.1540.061
Log-total clearance of creatinine (L/week)0.0730.379
Peritoneal clearance of creatinine (L/week)−0.0190.817
Carotid-femoral PWV (m/s)0.398*
Data of PD vintage, triglyceride, glucose, iPTH, total clearance of creatinine, and lipoprotein(a) levels showed skewed distribution and, therefore, were log-transformed before analysis. PD – peritoneal dialysis; SBP – systolic blood pressure; DBP – diastolic blood pressure; BUN – blood urea nitrogen; iPTH – intact parathyroid hormone; Weekly Kt/V – weekly fractional clearance index for urea; PWV – pulse wave velocity.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750