29 May 2024 : Clinical Research
A Retrospective Study of the Presentation, Diagnosis, Management, and Outcomes of 27 Patients with Osteogenesis Imperfecta at a Single Center in Türkiye
Mehmet Yiğit Gökmen
1ABCDEF*, Akif Mirioğlu 2E, Buğra Kundakçı2E, İbrahim Boğa3BE, Ömer Sunkar Biçer2ACE
DOI: 10.12659/MSM.944364
Med Sci Monit 2024; 30:e944364
Table 5 Distribution of complications and treatments according to genetic mutation types.
| Complications | p | Treatments | p | |||
|---|---|---|---|---|---|---|
| Yesn (%) | Non (%) | Surgical | Conservative | |||
| COL1A1 | 6 (31.6) | 49 (43.8) | 22 (61.1) | 33 (34.7) | ||
| COL1A2 | 2 (10.5) | 14 (12.5) | 0 (0.0) | 16 (16.8) | ||
| SERPINF1 | 1 (5.3) | 7 (6.3) | 3 (8.3) | 5 (5.3) | ||
| Non-COL1A1-COL1A2 | 10 (52.6) | 42 (37.5) | 11 (30.6) | 41 (43.2) | ||
| G>A heterozygous | 6 (31.6) | 29 (25.9) | 14 (38.9) | 21 (21.1) | ||
| Others | 3 (15.8) | 41 (36.6) | 11 (30.6) | 33 (34.7) | ||
| Undetermined | 10 (52.6) | 42 (37.5) | 11 (30.6) | 41 (43.6) | ||