20 August 2024 : Clinical Research
Lower Serum ATG7 Levels Linked to Insulin Resistance in Women with Polycystic Ovary Syndrome
Ling Lu1CDE, Baohua Wu1BCF, Cong Peng1BCF, Wei Zhang1BCF, Yutai Zhao1BCE, Chaolin Huang1AE*, Yingfei Long1ABDDOI: 10.12659/MSM.944556
Med Sci Monit 2024; 30:e944556
Table 1 Demographic data and biochemical parameters of the study population.
| Parameters | PCOS patients | Control individuals | p-value |
|---|---|---|---|
| Age (years) | 25.41±3.52 | 26.23±3.81 | 0.211 |
| BMI (kg/m) | 25.34±2.73 | 22.25±3.23 | |
| Menstrual cycle (days) | 74.52±4.72 | 30.37±2.82 | |
| Antral follicle count | 12±2.31 | 4±0.42 | |
| LH/FSH | 4.32±0.31 | 1.08±0.06 | |
| Testosterone (nmol/L) | 3.27±0.43 | 0.82±0.02 | |
| AMH (ng/ml) | 15.43±1.47 | 5.72±0.89 | |
| Fasting insulin (mU/L) | 18.21±3.12 | 7.63±0.67 | |
| DHEA (μmol/L) | 6.49±2.81 | 4.61±0.92 | |
| TGs (mmol/L) | 1.37±0.21 | 0.82±0.03 | |
| LDL-C (mmol/L) | 3.27±0.69 | 2.09±0.62 | |
| TC (mmol/L) | 4.52±0.81 | 3.72±0.51 | |
| HOMA-IR | 3.82±0.35 | 1.63±0.16 | |
| HDL-C (mmol/L) | 1.21±0.35 | 1.19±0.16 | 0.146 |
| FSH (IU/L) | 7.94±1.12 | 6.14±0.57 | |
| LH (IU/L) | 8.36±1.04 | 2.75±1.23 | |
| ATG7 (ng/ml) | 16.23±3.19 | 42.34±5.26 | |
| Data are analyzed by an independent samples t-test. A p | |||