20 August 2024 : Clinical Research
Lower Serum ATG7 Levels Linked to Insulin Resistance in Women with Polycystic Ovary Syndrome
Ling Lu1CDE, Baohua Wu1BCF, Cong Peng1BCF, Wei Zhang1BCF, Yutai Zhao1BCE, Chaolin Huang1AE*, Yingfei Long1ABDDOI: 10.12659/MSM.944556
Med Sci Monit 2024; 30:e944556
Table 2 Associations of serum ATG7 levels with hormone levels, insulin resistance, and lipid metabolic indices of PCOS patients.
| Variable | Serum ATG7 Levels | |||
|---|---|---|---|---|
| Pearson’s correlation analysis | Multiple linear logistic regression analysis | |||
| r | p-value | r | p-value | |
| Age (years) | 0.132 | 0.098 | 0.107 | 0.315 |
| BMI (kg/m) | −0.123 | 0.102 | 0.172 | 0.071 |
| TG (mmol/L) | −0.461 | −0.122 | 0.415 | |
| TC (mmol/L) | −0.387 | 0.168 | 0.114 | |
| LDL-C (mmol/L) | −0.564 | −0.378 | 0.082 | |
| HDL-C (mmol/L) | 0.132 | 0.371 | 0.216 | 0.225 |
| Fasting insulin (mU/L) | −0.614 | −0.356 | 0.213 | |
| LH (IU/L) | −0.317 | 0.231 | 0.152 | |
| Testosterone (nmol/L) | −0.714 | −0.625 | ||
| AMH (ng/ml) | −0.683 | −0.317 | 0.202 | |
| HOMA-IR | −0.687 | −0.514 | ||
| FSH (IU/L) | 0.143 | 0.302 | −0.492 | 0.308 |
| DHEA (μmol/L) | −0.475 | 0.091 | −0.177 | 0.127 |
| The multiple linear logistic regression analysis was adjusted for TG, TC, LDL-C, fasting insulin, LH, testosterone, AMH, and HOMA-IR. A p | ||||