23 May 2024 : Database Analysis
MRTO4 Enhances Glycolysis to Facilitate HCC Progression by Inhibiting ALDOB
Yongyuan Zheng1ABCD, Yansong Huang1CDE, Weibing Li1CD, Hongqiu Cheng1AEG*DOI: 10.12659/MSM.944685
Med Sci Monit 2024; 30:e944685
Table 5 Gene sets enriched in the high MRTO4 expression phenotype by GO & KEGG analysis.
| Ontology | ID | Description | GeneRatio | BgRatio | P value | P.adjust |
|---|---|---|---|---|---|---|
| BP | GO: 0030388 | Fructose 1,6-bisphosphate metabolic process | 2/33 | 10/18800 | * | 0.0916 |
| BP | GO: 0006000 | Fructose metabolic process | 2/33 | 13/18800 | * | 0.0916 |
| MF | GO: 0005319 | Lipid transporter activity | 4/34 | 159/18410 | * | * |
| KEGG | hsa00030 | Pentose phosphate pathway | 2/15 | 30/8164 | * | * |
| KEGG | hsa00051 | Fructose and mannose metabolism | 2/15 | 33/8164 | * | * |
| KEGG | hsa00270 | Cysteine and methionine metabolism | 2/15 | 51/8164 | * | * |
| KEGG | hsa00010 | Glycolysis/gluconeogenesis | 2/15 | 67/8164 | * | 0.0550 |
| KEGG | hsa03320 | PPAR signaling pathway | 2/15 | 75/8164 | * | 0.0550 |
| Bold values indicate * P BP – biological process; CC – cellular component; MF – molecular function. | ||||||